Depressed natural killer cell activity in patients with hepatocellular carcinoma in vitro effects of interferon and levamisole

K Son, M Kew, AR Rabson - Cancer, 1982 - Wiley Online Library
Enriched lymphocytes from patients with primary hepatocellular carcinoma showed
considerably reduced natural cytotoxicity against two established hepatoma cell lines and …

Effect of histamine and histamine antagonists on natural and antibody-dependent cellular cytotoxicity of human lymphocytes in vitro

MPN Nair, SA Schwartz - Cellular immunology, 1983 - Elsevier
The in vitro effect of histamine and its antagonists, cimetidine and clemastine fumarate, on
natural killer (NK) and antibody-dependent cellular Cytotoxicity (ADCC) activities of human …

Systemic administration of human leukocyte interferon to melanoma patients. II. Cellular events associated with changes in natural killer cytotoxicity

SH Golub, P D'Amore, M Rainey - Journal of the National …, 1982 - academic.oup.com
Abstract Treatment of patients with malignant melanoma with daily doses of human
leukocyte interferon (IFN) resulted in natural killer (NK) cytotoxicity that increased during the …

Kinetic analysis of human spontaneous cell-mediated cytotoxicity

SB Pollack, SL Emmons - The Journal of Immunology, 1979 - journals.aai.org
We tested whether the kinetics of human spontaneous cell-mediated cytotoxicity (SCMC) fit
the enzyme-substrate model for cellular cytotoxicity. As predicted by the model, the maximal …

Suppression of spleen natural killing activity induced by BCG

M Ito, P Ralph, MAS Moore - Clinical Immunology and Immunopathology, 1980 - Elsevier
Mycobacterium Bacille Calmette-Guerin (BCG) injected into mice ip depressed splenic
natural killing (NK) of YAC tumor targets 5 to 14 days after injection. Suppression of spleen …

Immunoregulation of human natural killer cells (NK) by corticosteroids: inhibitory effect of culture supernatants

MPN Nair, SA Schwartz - Journal of allergy and clinical immunology, 1988 - Elsevier
Peripheral blood lymphocytes were separated into HNK-l+ and HNK-l− subpopulations and
examined for the effects of prednisolone (PRD) on natural killer cell activities in vitro …

Relationship of the distribution of leu-2+ cells with suppressor cell activities in the spleen and lymphnodes from gastric cancer

T Toge, Y Seto, K Kuroi, H Yamada, K Aratani… - The Japanese journal of …, 1987 - Springer
Tissue distributions of Leu-2+ cells in the spleen and draining lymphnodes in cases of
clinical gastric cancer were investigated, with special reference to suppressor cell function …

Natural killer-like activity induced in spleen by IP injection of BCG

Y Pioch, M Gerber, B Serrou - Cancer Immunology, Immunotherapy, 1979 - Springer
Cytotoxic cells comparable to NK cells were induced in the spleens of C57B1/6 mice after IP
injection of BCG. This activity was directed against target cells that were not spontaneously …

Antibody-dependent cell-mediated cytotoxicity: Effectors, Signals, and Mechanisms

EW Fuson, RA Hubbard, DG Sugantharaj… - Survey of Immunologic …, 1983 - Springer
In vitro studies of lymphocyte-mediated cytotoxicity may be easily divided into experiments
designed to investigate the lytic activity of primed (presensitized) or nonprimed cells. Studies …

Cyclophosphamide inhibits antibody-dependent cellular cytotoxicity (ADCC) suppression exerted by lymph node cells

MS Palermo, M Giordano, S Olabuenaga, MA Isturiz - Cellular immunology, 1985 - Elsevier
Abstract The effect of Cyclophosphamide (Cy) on suppression of antibody-dependent
cellular Cytotoxicity (ADCC) by lymph node cells (LNC) was evaluated. The results show …