In the category of mature B-cell neoplasms, splenic B-cell lymphoma and leukemia were
clearly identified and include four distinct entities: hairy cell leukemia (HCL), splenic …

Simple Summary Artificial intelligence (AI) is a field that combines computer science with
robust datasets to solve problems. AI in medicine uses machine learning and deep learning …

Simple Summary Composite/synchronous lymphoma is a rare entity, for which the
histopathological diagnosis is difficult due to the co-occurrence of at least two lymphomas …

The variant form of hairy cell leukaemia (HCL‐V) is a rare disease very different from hairy
cell leukaemia (HCL), which is a very well‐defined entity. The 5th WHO edition (Leukemia …

Splenic marginal zone lymphoma (SMZL) is a rare, predominantly indolent B-cell lymphoma
constituting fewer than 2% of lymphoid neoplasms. However, around 30% of patients have a …

Primary splenic lymphoma (PSL) is a rare malignancy representing about 1% of all
lymphoproliferative disorders, when using a strict definition that allows only involvement of …

The monoclonal B-cell lymphocytosis (MBL) introduced as new entities in the 2008 WHO
classification, are defined by circulating B-cell clone< 5.109/L without organomegaly and …

The diagnosis of Hairy Cell Leukemia and HCL-like diosrders, including HCL variant (vHCL)
and Splenic Diffuse Red Pulp Lymphoma (SDRPL), is based on the examination of the …

Composite/synchronous lymphoma is an uncommon condition that presents a challenge in
histopathological diagnosis due to the simultaneous appearance of two or more lymphomas …

Tumors derived from B-lymphocytes at their various stage of maturation and differentiation
(human B-cell lymphomas and leukemias) are the commonest hematological malignancies …