Risk factors for endemic chronic kidney disease of unknown etiology in Sri Lanka: Retrospect of water security in the dry zone

O Hettithanthri, S Sandanayake… - Science of the Total …, 2021 - Elsevier
The prevalence of chronic kidney disease of unknown etiology (CKDu) is receiving
considerable attention due to the serious threat to human health throughout the world …

[HTML][HTML] A comparative review: Chronic Kidney Disease of unknown etiology (CKDu) research conducted in Latin America versus Asia

JH Redmon, KE Levine, J Lebov, J Harrington… - Environmental …, 2021 - Elsevier
Introduction The incidence of chronic kidney disease of unknown or uncertain etiology
(CKDu) is recognized as a global health crisis. Research to pinpoint the risk factors …

Possible links between groundwater geochemistry and chronic kidney disease of unknown etiology (CKDu): an investigation from the Ginnoruwa region in Sri Lanka

S Balasooriya, H Munasinghe, AT Herath… - Exposure and …, 2020 - Springer
Since at least two decades, Chronic Kidney Disease of Uncertain Etiology (CKDu) has
become an increasingly discussed health issue in Sri Lanka and as well as in other tropical …

Exposure to Sri Lanka's local groundwater in a CKDu prevalent area causes kidney damage in zebrafish

YF Yang, WG Li, PP Wen, PP Jia, YZ Li, TY Li, DS Pei - Aquatic Toxicology, 2022 - Elsevier
How local groundwater induces chronic kidney disease of unknown etiology (CKDu) in Sri
Lanka is still elusive. This study aims to elucidate the impacts of Sri Lanka's local …

[HTML][HTML] Burden of end-stage renal disease of undetermined etiology in Africa

T Fiseha, NJ Osborne - Renal Replacement Therapy, 2023 - Springer
In the last two decades, there have been increasing recognition of excess cases of end-
stage renal disease (ESRD) requiring renal replacement therapy without common …

[HTML][HTML] Impacts of climate change and heat stress on farmworkers' health: A scoping review

M El Khayat, DA Halwani, L Hneiny… - Frontiers in public …, 2022 - frontiersin.org
Due to the continuous rise of global temperatures and heatwaves worldwide as a result of
climate change, concerns for the health and safety of working populations have increased …

Using water quality and isotope studies to inform research in chronic kidney disease of unknown aetiology endemic areas in Sri Lanka

C Nikagolla, KT Meredith, LA Dawes, RB Banati… - Science of the Total …, 2020 - Elsevier
Abstract Chronic Kidney Disease of unknown aetiology (CKDu) is a major public health
concern in dry climatic, agricultural regions of Sri Lanka. The chemistry of groundwater (the …

[HTML][HTML] Chronic dehydration induces injury pathways in rats, but does not mimic histopathology of chronic interstitial nephritis in agricultural communities

G Schreurs, S Maudsley, C Nast, M Praet… - Scientific Reports, 2023 - nature.com
CINAC-patients present renal proximal tubular cell lysosomal lesions which are also
observed in patients experiencing calcineurin inhibitor (CNI) nephrotoxicity, suggesting that …

Chronic kidney disease of undetermined etiology around the world

M Floris, N Lepori, A Angioi, G Cabiddu… - Kidney and Blood …, 2021 - karger.com
Background: Epidemics of chronic kidney disease of uncertain etiology (CKDu) are
occurring on the Pacific coast of Central America, in Sri Lankan and Indian agricultural …

[HTML][HTML] A systematic study of the prevalence and risk factors of CKD in Uddanam, India

B Gummidi, O John, A Ghosh, GK Modi… - Kidney International …, 2020 - Elsevier
Introduction Despite reports of a high prevalence of chronic kidney disease (CKD) from the
coastal Uddanam region of Andhra Pradesh, India, there are no accurate data on the …