[HTML][HTML] Mesenchymal stem cell-derived exosomes: therapeutic opportunities and challenges for spinal cord injury

W Liu, Z Ma, J Li, X Kang - Stem cell research & therapy, 2021 - Springer
Spinal cord injury (SCI) often leads to serious motor and sensory dysfunction of the limbs
below the injured segment. SCI not only results in physical and psychological harm to …

Polymer scaffolds facilitate spinal cord injury repair

Q Zhang, B Shi, J Ding, L Yan, JP Thawani, C Fu… - Acta biomaterialia, 2019 - Elsevier
During the past decades, improving patient neurological recovery following spinal cord
injury (SCI) has remained a challenge. An effective treatment for SCI would not only reduce …

Injectable, adhesive, self-healing and conductive hydrogels based on MXene nanosheets for spinal cord injury repair

Q Yu, S Jin, S Wang, H Xiao, Y Zhao - Chemical Engineering Journal, 2023 - Elsevier
In situ reconstruction of the micro-environment through multifunctional hydrogel verified to
be an efficient strategy to accelerate spinal cord injury (SCI) repair. However, it remains …

[HTML][HTML] Applications of various types of nanomaterials for the treatment of neurological disorders

A Waris, A Ali, AU Khan, M Asim, D Zamel, K Fatima… - Nanomaterials, 2022 - mdpi.com
Neurological disorders (NDs) are recognized as one of the major health concerns globally.
According to the World Health Organization (WHO), neurological disorders are one of the …

Drug delivery, cell-based therapies, and tissue engineering approaches for spinal cord injury

S Kabu, Y Gao, BK Kwon, V Labhasetwar - Journal of Controlled Release, 2015 - Elsevier
Spinal cord injury (SCI) results in devastating neurological and pathological consequences,
causing major dysfunction to the motor, sensory, and autonomic systems. The primary …

Recent advancements of nanomedicine in neurodegenerative disorders theranostics

S Mukherjee, VS Madamsetty… - Advanced Functional …, 2020 - Wiley Online Library
Recent times have witnessed an upsurge in the incidence of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Prion disease, and …

Selenium-doped carbon quantum dots efficiently ameliorate secondary spinal cord injury via scavenging reactive oxygen species

W Luo, Y Wang, F Lin, Y Liu, R Gu, W Liu… - International journal of …, 2020 - Taylor & Francis
Background: The excess production of reactive oxygen species (ROS) after traumatic spinal
cord injury (TSCI) has been identified as a leading cause of secondary injury, which can …

[HTML][HTML] The application of biomaterials in spinal cord injury

C Feng, L Deng, YY Yong, JM Wu, DL Qin, L Yu… - International journal of …, 2023 - mdpi.com
The spinal cord and the brain form the central nervous system (CNS), which is the most
important part of the body. However, spinal cord injury (SCI) caused by external forces is …

Recent advances in nanotherapeutic strategies for spinal cord injury repair

YH Song, NK Agrawal, JM Griffin, CE Schmidt - Advanced drug delivery …, 2019 - Elsevier
Spinal cord injury (SCI) is a devastating and complicated condition with no cure available.
The initial mechanical trauma is followed by a secondary injury characterized by …

Polysialic-acid-based micelles promote neural regeneration in spinal cord injury therapy

XJ Wang, CH Peng, S Zhang, XL Xu, GF Shu, J Qi… - Nano Letters, 2019 - ACS Publications
Spinal cord injury (SCI) routinely causes the immediate loss and disruption of neurons
followed by complicated secondary injuries, including inflammation, oxidative stress, and …