Preemptive interferon-α therapy could protect against relapse and improve survival of acute myeloid leukemia patients after allogeneic hematopoietic stem cell …

MZ Shen, XH Zhang, LP Xu, Y Wang, CH Yan… - Frontiers in …, 2022 - frontiersin.org
For allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients, preemptive
interferon-α (IFN-α) therapy is considered as a useful method to eliminate the minimal …

Haploidentical transplantation is associated with better overall survival when compared to single cord blood transplantation: an EBMT-Eurocord study of acute …

F Giannotti, M Labopin, R Shouval, J Sanz… - Journal of hematology & …, 2018 - Springer
Background Thiotepa-busulfan-fludarabine (TBF) is a widely used conditioning regimen in
single umbilical cord blood transplantation (SUCBT). More recently, it was introduced in the …

Modified combination of anti-thymocyte globulin (ATG) and post-transplant cyclophosphamide (PTCy) as compared with standard ATG protocol in haploidentical …

M Barkhordar, A Kasaeian, G Janbabai… - Frontiers in …, 2022 - frontiersin.org
In haploidentical peripheral blood stem cell transplantation (haplo-PBSCT), the combination
of anti-thymocyte globulin and post-transplant cyclophosphamide (ATG/PTCy) has a …

Eltrombopag is an effective and safe therapy for refractory thrombocytopenia after haploidentical hematopoietic stem cell transplantation

H Fu, X Zhang, T Han, X Mo, Y Wang, H Chen… - Bone Marrow …, 2019 - nature.com
Refractory thrombocytopenia is a frequent and severe complication after haploidentical
allogeneic hematopoietic stem cell transplantation (haplo-HSCT) and lacks effective …

Clinical features of DDX41 mutation-related diseases: a systematic review with individual patient data

Z Wan, B Han - Therapeutic Advances in Hematology, 2021 - journals.sagepub.com
Background: DDX41 serves as a DNA sensor in innate immunity and mutated DDX41 is
pathogenic, mainly for myeloid neoplasms. Methods: In this study,“DDX41” was searched in …

Poor graft function after allogeneic hematopoietic stem cell transplantation—an old complication with new insights☆

Y Kong - Seminars in Hematology, 2019 - Elsevier
Poor graft function (PGF), characterized by pancytopenia, is a life-threatening complication
following allogeneic hematopoietic stem cell transplantation (allo-HSCT). PGF has become …

Analysis benefits of a second allo-HSCT after CAR-T cell therapy in patients with relapsed/refractory B-cell acute lymphoblastic leukemia who relapsed after transplant

X Cao, J Zhang, Y Zhao, M Xiong, J Zhou, Y Lu… - Frontiers in …, 2023 - frontiersin.org
Background Chimeric antigen receptor (CAR) T-cell therapy has demonstrated high initial
complete remission (CR) rates in B-cell acute lymphoblastic leukemia (B-ALL) patients …

Haploidentical stem cell transplantation for acute myeloid leukemia: current therapies, challenges and future prospective

YJ Chang, XY Zhao, XJ Huang - Frontiers in Oncology, 2021 - frontiersin.org
Haploidentical stem cell transplantation (haplo-SCT), an alternative donor source, offers a
curative therapy for patients with acute myeloid leukemia (AML) who are transplant …

Early myeloid-derived suppressor cells (HLA-DR/lowCD33+CD16) expanded by granulocyte colony-stimulating factor prevent acute graft-versus-host disease …

K Wang, M Lv, YJ Chang, XY Zhao, XS Zhao… - Journal of hematology & …, 2019 - Springer
Introduction Myeloid-derived suppressor cells (MDSCs) are proposed to control graft-versus-
host disease (GVHD) in allogeneic hematopoietic stem cell transplantation (allo-HSCT) …

Comparisons of long-term survival and safety of haploidentical hematopoietic stem cell transplantation after CAR-T cell therapy or chemotherapy in pediatric patients …

G Hu, Y Cheng, Y Zuo, Y Chang, P Suo, Y Jia… - Frontiers in …, 2022 - frontiersin.org
Measurable residual disease (MRD) positivity before haploidentical hematopoietic stem cell
transplantation (haplo-HSCT) is an independent prognostic factor in determining outcomes …