Non-coding RNAs in disease: from mechanisms to therapeutics
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
Exercise training maintains cardiovascular health: signaling pathways involved and potential therapeutics
Exercise training has been widely recognized as a healthy lifestyle as well as an effective
non-drug therapeutic strategy for cardiovascular diseases (CVD). Functional and …
non-drug therapeutic strategy for cardiovascular diseases (CVD). Functional and …
Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential
TG Martin, MA Juarros, LA Leinwand - Nature Reviews Cardiology, 2023 - nature.com
Left ventricular hypertrophy is a leading risk factor for cardiovascular morbidity and mortality.
Although reverse ventricular remodelling was long thought to be irreversible, evidence from …
Although reverse ventricular remodelling was long thought to be irreversible, evidence from …
Molecular mechanisms of exercise contributing to tissue regeneration
J Chen, R Zhou, Y Feng, L Cheng - Signal Transduction and Targeted …, 2022 - nature.com
Physical activity has been known as an essential element to promote human health for
centuries. Thus, exercise intervention is encouraged to battle against sedentary lifestyle …
centuries. Thus, exercise intervention is encouraged to battle against sedentary lifestyle …
Exercise-induced circular RNA circUtrn is required for cardiac physiological hypertrophy and prevents myocardial ischaemia–reperfusion injury
L Wang, J Feng, X Feng, D Meng, X Zhao… - Cardiovascular …, 2023 - academic.oup.com
Aims Regular exercise training benefits cardiovascular health and effectively reduces the
risk for cardiovascular disease. Circular RNAs (circRNAs) play important roles in cardiac …
risk for cardiovascular disease. Circular RNAs (circRNAs) play important roles in cardiac …
Animal models of exercise from rodents to pythons
MH Hastings, JJ Herrera, JS Guseh, B Atlason… - Circulation …, 2022 - Am Heart Assoc
Acute and chronic animal models of exercise are commonly used in research. Acute
exercise testing is used, often in combination with genetic, pharmacological, or other …
exercise testing is used, often in combination with genetic, pharmacological, or other …
Exercise Promotes Tissue Regeneration: Mechanisms Involved and Therapeutic Scope
Exercise has well-recognized beneficial effects on the whole body. Previous studies suggest
that exercise could promote tissue regeneration and repair in various organs. In this review …
that exercise could promote tissue regeneration and repair in various organs. In this review …
[HTML][HTML] Long noncoding RNAs in cardiovascular disease
A Kohlmaier, LM Holdt, D Teupser - Current opinion in cardiology, 2023 - journals.lww.com
Summary lncRNA research is passing the stage of enumerating lncRNAs or recording
simplified on-off expression switches. Mechanistic analyses are starting to reveal …
simplified on-off expression switches. Mechanistic analyses are starting to reveal …
Extracellular non-coding RNAs in cardiovascular diseases
Z Jiapaer, C Li, X Yang, L Sun, E Chatterjee, L Zhang… - Pharmaceutics, 2023 - mdpi.com
Cardiovascular diseases (CVDs) remain the world's leading cause of death despite the best
available healthcare and therapy. Emerging as a key mediator of intercellular and inter …
available healthcare and therapy. Emerging as a key mediator of intercellular and inter …
[HTML][HTML] Revisiting skeletal myopathy and exercise training in heart failure: emerging role of myokines
Exercise intolerance remains a major unmet medical need in patients with heart failure (HF).
Skeletal myopathy is currently considered as the major limiting factor for exercise capacity in …
Skeletal myopathy is currently considered as the major limiting factor for exercise capacity in …