Targeting metabolic diseases: the role of nutraceuticals in modulating oxidative stress and inflammation

A Dama, K Shpati, P Daliu, S Dumur, E Gorica… - Nutrients, 2024 - mdpi.com
The escalating prevalence of metabolic and cardiometabolic disorders, often characterized
by oxidative stress and chronic inflammation, poses significant health challenges globally …

[HTML][HTML] The Transcription Factor HOXA5: Novel Insights into Metabolic Diseases and Adipose Tissue Dysfunction

L Parrillo, R Spinelli, M Longo, F Zatterale… - Cells, 2023 - mdpi.com
The transcription factor HOXA5, from the HOX gene family, has long been studied due to its
critical role in physiological activities in normal cells, such as organ development and body …

Clinical classification of obesity and implications for metabolic dysfunction-associated fatty liver disease and treatment

Y Ding, Q Deng, M Yang, H Niu, Z Wang… - … Syndrome and Obesity, 2023 - Taylor & Francis
Obesity, and metabolic dysfunction-associated fatty liver disease (MAFLD) have reached
epidemic proportions globally. Obesity and MAFLD frequently coexist and act synergistically …

Unraveling the complex roles of macrophages in obese adipose tissue: an overview

C Peng, J Chen, R Wu, H Jiang, J Li - Frontiers of medicine, 2024 - Springer
Macrophages, a heterogeneous population of innate immune cells, exhibit remarkable
plasticity and play pivotal roles in coordinating immune responses and maintaining tissue …

[HTML][HTML] Exploring the Link between Oxidative Stress, Selenium Levels, and Obesity in Youth

TO Bizerea-Moga, L Pitulice… - International Journal of …, 2024 - mdpi.com
Obesity is a worldwide increasing concern. Although in adults this is easily estimated with
the body mass index, in children, who are constantly growing and whose bodies are …

[HTML][HTML] Targeting systemic inflammation in metabolic disorders. A therapeutic candidate for the prevention of cardiovascular diseases?

E Domingo, P Marques, V Francisco, L Piqueras… - Pharmacological …, 2024 - Elsevier
Cardiovascular disease (CVD) remains the leading cause of death and disability worldwide.
While many factors can contribute to CVD, atherosclerosis is the cardinal underlying …

[HTML][HTML] Antioxidant and Anti-Inflammatory Effects of Agarum cribrosum Extract and Its Fractions in LPS-Induced RAW 264.7 Macrophages

MB Kim, H Lee, T Vance, SG Lee - Applied Sciences, 2023 - mdpi.com
Excessive oxidative stress and chronic inflammation are implicated in the pathogenesis of
chronic inflammation diseases. The purpose of this study was to determine whether the …

[HTML][HTML] Chemerin in Participants with or without Insulin Resistance and Diabetes

L Zhao, J Zhou, F Abbasi, M Fathzadeh, JW Knowles… - Biomedicines, 2024 - mdpi.com
Chemerin is a chemokine/adipokine, regulating inflammation, adipogenesis and energy
metabolism whose activity depends on successive proteolytic cleavages at its C-terminus …

Progress in the contrary effects of glucagon-like peptide-1 and chemerin on obesity development

Q Zhang, J Ye, X Wang - Experimental Biology and Medicine, 2023 - journals.sagepub.com
Glucagon-like peptide-1 (GLP-1), secreted by intestinal L-cells, plays a pivotal role in the
modulation of β-cell insulin secretion in a glucose-dependent manner, concurrently …

Konjac glucomannan exerts regulatory effects on macrophages and its applications in biomedical engineering

X Pan, Q Zong, C Liu, H Wu, B Fu, Y Wang, W Sun… - Carbohydrate …, 2024 - Elsevier
Konjac glucomannan (KGM) molecular chains contain a small amount of acetyl groups and
a large number of hydroxyl groups, thereby exhibiting exceptional water retention and gel …