Adiponectin: role in physiology and pathophysiology

TMD Nguyen - International journal of preventive medicine, 2020 - journals.lww.com
Background: Chronic diseases such as diabetes have an adverse effect on the quality of life
(QOL) of patients. It has been shown physical activity can improve the quality of life. Aims …

Obesity-induced changes in adipose tissue microenvironment and their impact on cardiovascular disease

JJ Fuster, N Ouchi, N Gokce, K Walsh - Circulation research, 2016 - Am Heart Assoc
Obesity is causally linked with the development of cardiovascular disorders. Accumulating
evidence indicates that cardiovascular disease is the collateral damage of obesity-driven …

Metabolic messengers: adiponectin

LG Straub, PE Scherer - Nature Metabolism, 2019 - nature.com
Adiponectin, first described in the mid-1990s, is one of the most widely studied adipokines to
date. Studies of its regulation, biogenesis and physiological effects have yielded great …

Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue

SN Saxton, BJ Clark, SB Withers… - Physiological …, 2019 - journals.physiology.org
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

Adiponectin signaling and function in insulin target tissues

H Ruan, LQ Dong - Journal of molecular cell biology, 2016 - academic.oup.com
Obesity-linked type 2 diabetes is one of the paramount causes of morbidity and mortality
worldwide, posing a major threat on human health, productivity, and quality of life. Despite …

Adipose tissue dysfunction and obesity-related male hypogonadism

VA Genchi, E Rossi, C Lauriola, R D'Oria… - International Journal of …, 2022 - mdpi.com
Obesity is a chronic illness associated with several metabolic derangements and
comorbidities (ie, insulin resistance, leptin resistance, diabetes, etc.) and often leads to …

Adipokines in inflammation and metabolic disease

N Ouchi, JL Parker, JJ Lugus, K Walsh - Nature reviews immunology, 2011 - nature.com
The worldwide epidemic of obesity has brought considerable attention to research aimed at
understanding the biology of adipocytes (fat cells) and the events occurring in adipose …

Adiponectin regulation and function

H Fang, RL Judd - Comprehensive Physiology, 2011 - Wiley Online Library
Adipose tissue is now recognized as an important endocrine organ, capable of secreting a
large number of endocrine factors which regulate a wide variety of physiological functions …

Adipokines and insulin resistance

K Rabe, M Lehrke, KG Parhofer, UC Broedl - Molecular medicine, 2008 - Springer
Obesity is associated with an array of health problems in adult and pediatric populations.
Understanding the pathogenesis of obesity and its metabolic sequelae has advanced …

Adipose tissue: the new endocrine organ? A review article

SE Wozniak, LL Gee, MS Wachtel… - Digestive diseases and …, 2009 - Springer
Fat is either white or brown, the latter being found principally in neonates. White fat, which
comprises adipocytes, pre-adipocytes, macrophages, endothelial cells, fibroblasts, and …