Thrombin preconditioning improves the therapeutic efficacy of mesenchymal stem cells in severe intraventricular hemorrhage induced neonatal rats

SY Jung, YE Kim, WS Park, SY Ahn, DK Sung… - International Journal of …, 2022 - mdpi.com
Severe intraventricular hemorrhage (IVH) remains a major cause of high mortality and
morbidity in extremely preterm infants. Mesenchymal stem cell (MSC) transplantation is a …

Fetal oxygenation from the 23rd to the 36th week of gestation evaluated through the umbilical cord blood gas analysis

L Filippi, F Pascarella, A Pini, M Cammalleri… - International Journal of …, 2023 - mdpi.com
The embryo and fetus grow in a hypoxic environment. Intrauterine oxygen levels fluctuate
throughout the pregnancy, allowing the oxygen to modulate apparently contradictory …

Protecting the premature brain: current evidence-based strategies for minimising perinatal brain injury in preterm infants

CL Lea, A Smith-Collins, K Luyt - Archives of Disease in Childhood-Fetal …, 2017 - fn.bmj.com
Improving neurodevelopmental outcome for preterm infants is an important challenge for
neonatal medicine. The disruption of normal brain growth and neurological development is …

Are thrombocytopenia and platelet transfusions associated with major bleeding in preterm neonates? A systematic review

SF Fustolo-Gunnink, EJ Huisman, JG Van der Bom… - Blood reviews, 2019 - Elsevier
Over 75% of severely thrombocytopenic preterm neonates receive platelet transfusions to
prevent bleeding, but transfusion guidelines are based mainly on expert opinion. The aim of …

Fetal intracranial hemorrhage: role of fetal MRI

L Sanapo, MT Whitehead, DI Bulas… - Prenatal …, 2017 - Wiley Online Library
Objective To date, prenatal diagnosis of intracranial hemorrhage (ICH) is mainly based on
ultrasound (US) findings rather than magnetic resonance imaging (MRI). We aimed to …

Differences in subependymal vein anatomy may predispose preterm infants to GMH–IVH

D Tortora, M Severino, M Malova, A Parodi… - Archives of Disease in …, 2018 - fn.bmj.com
Background and purpose The anatomy of the deep venous system plays an important role in
the pathogenesis of brain lesions in the preterm brain as shown by different histological …

Mesenchymal stem cells: the magic cure for intraventricular hemorrhage?

WS Park, SY Ahn, SI Sung, JY Ahn… - Cell …, 2017 - journals.sagepub.com
Severe intraventricular hemorrhage (IVH) remains a major cause of mortality and long-term
neurologic morbidities in premature infants, despite recent advances in neonatal intensive …

Prenatal development of the human entorhinal cortex

G Šimić, Ž Krsnik, V Knezović, Z Kelović… - Journal of …, 2022 - Wiley Online Library
Little is known about the development of the human entorhinal cortex (EC), a major hub in a
widespread network for learning and memory, spatial navigation, high‐order processing of …

Blood–brain barrier and foetal-onset hydrocephalus, with a view on potential novel treatments beyond managing CSF flow

M Guerra, JL Blázquez, EM Rodríguez - Fluids and Barriers of the CNS, 2017 - Springer
Despite decades of research, no compelling non-surgical therapies have been developed
for foetal hydrocephalus. So far, most efforts have pointed to repairing disturbances in the …

Neuroprotective effects of betulinic acid hydroxamate in intraventricular hemorrhage-induced brain damage in immature rats

A Del Pozo, L Silva, A Romero, M De Hoz-Rivera… - Nutrients, 2022 - mdpi.com
Intraventricular hemorrhage (IVH) is an important cause of long-term disability in extremely
preterm infants, with no current treatment. We aimed to study in an IVH model in immature …