Abstract Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR)
signaling is one of the most important intracellular pathways, which can be considered as a …

The phospatidylinositol-3 kinase (PI3K) pathway is a crucial intracellular signaling pathway
which is mutated or amplified in a wide variety of cancers including breast, gastric, ovarian …

Background Risk stratification or progression in prostate cancer is performed with the
support of clinical-pathological data such as the sum of the Gleason score and serum levels …

The central dogma of molecular biology states that the functions of RNA revolve around
protein translation. Until the last decade, most researches were geared towards …

The regulation of inflammation is pivotal for preventing the development or reoccurrence of
multiple sclerosis (MS). A biased ratio of high‐M1 versus low‐M2 polarized microglia is a …

It is increasingly recognised that lncRNAs play essential regulatory roles in fundamental
biological processes and, consequently, that their dysregulation may contribute to major …

The traditional view of genome organization has been upended in the last decade with the
discovery of vast amounts of non–protein-coding transcription. After initial concerns that this …

Background Epithelial ovarian cancer (EOC) is the malignant tumor of the female
reproductive system with the highest fatality rate. Tolerance of chemotherapeutic drugs like …

Exosomes are membranous vesicles containing various biomolecules including lncRNAs
which are involved in cellular communication and are secreted from many cells including …

Background Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related
death, especially in China. And the mechanism of its progression remains poorly …