What is polypharmacy? A systematic review of definitions

N Masnoon, S Shakib, L Kalisch-Ellett, GE Caughey - BMC geriatrics, 2017 - Springer
Background Multimorbidity and the associated use of multiple medicines (polypharmacy), is
common in the older population. Despite this, there is no consensus definition for …

An update on the clinical consequences of polypharmacy in older adults: a narrative review

JW Wastesson, L Morin, ECK Tan… - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Polypharmacy, the use of multiple medications by one individual, is
increasingly common among older adults. Caring for the growing number of older people …

[PDF][PDF] 2015 ESC Guidelines for the diagnosis and management of pericardial diseases

Y Adler, P Charron, M Imazio… - Polish Heart …, 2015 - journals.viamedica.pl
Osierdzie (z greckiego veri—wokół, kardiou—serce) stanowi zbudowaną z dwóch blaszek
workowatą strukturę, w której znajduje się serce i wychodzące z niego duże pnie …

Microemulsion utility in pharmaceuticals: Implications for multi-drug delivery

SP Callender, JA Mathews, K Kobernyk… - International journal of …, 2017 - Elsevier
Emulsion technology has been utilized extensively in the pharmaceutical industry. This
article presents a comprehensive review of the literature on an important subcategory of …

Medication review in hospitalised patients to reduce morbidity and mortality

M Christensen, A Lundh - Cochrane Database of Systematic …, 2016 - cochranelibrary.com
Background Pharmacotherapy in the elderly population is complicated by several factors
that increase the risk of drug‐related harms and less favourable effectiveness. The concept …

Impact of strategies to reduce polypharmacy on clinically relevant endpoints: a systematic review and meta‐analysis

T Johansson, ME Abuzahra, S Keller… - British journal of …, 2016 - Wiley Online Library
Aim The aim of the present study was to explore the impact of strategies to reduce
polypharmacy on mortality, hospitalization and change in number of drugs. Methods …

Factors associated with medication adherence in older patients: a systematic review

A Smaje, M Weston‐Clark, R Raj, M Orlu… - Aging …, 2018 - Wiley Online Library
Objective Medication adherence is a major challenge in the treatment of older patients;
however, they are under‐represented in research. We undertook a systematic review …

Acute, periprocedural and longterm antithrombotic therapy in older adults: 2022 Update by the ESC Working Group on Thrombosis

F Andreotti, T Geisler, JP Collet, B Gigante… - European Heart …, 2023 - academic.oup.com
The first international guidance on antithrombotic therapy in the elderly came from the
European Society of Cardiology Working Group on Thrombosis in 2015. This same group …

Adherence to therapy and adverse drug reactions: is there a link?

C Leporini, G De Sarro, E Russo - Expert opinion on drug safety, 2014 - Taylor & Francis
Introduction: Advances in biomedical technology and access to effective medications have
resulted in significant improvements in patient survival and quality of life. Patient adherence …

Management of hyperuricemia in asymptomatic patients: a critical appraisal

A Brucato, F Cianci, C Carnovale - European Journal of Internal Medicine, 2020 - Elsevier
While there is consensus on starting urate-lowering therapy (ULT) in cases of symptomatic
hyperuricemia, the frequent condition of asymptomatic hyperuricemia (AH) remains a …