Background: Low birth weight is associated with lower values for spirometry in adults but it is
not known if birth weight influences other measures of pulmonary function. It is also unclear …

BACKGROUND: Breast-feeding clearly protects against early wheezing, but recent data
suggest that it might increase later risk of atopic disease and asthma. OBJECTIVE: We …

Asthma is an increasing global health burden, especially in the western world. Public health
interventions are sought to lessen its prevalence or severity, and diet and nutrition have …

Background There is much interest in the possibility that perinatal factors may influence the
risk of disease in later life. We investigated the influence of maternal and perinatal factors on …

Background Breast milk contains many immunomodulatory factors (soluble CD14 (sCD14),
IgA and cytokines) with the potential to influence infant immune development. Objective To …

Although Canadian guidelines for the diagnosis and management of asthma have been
published over the last 15 years, 1–4 there has been little focus on issues relevant to asthma …

BACKGROUND: The literature regarding the association between breast-feeding and atopic
diseases has been contradictory. OBJECTIVE: We have assessed the relationship between …

BACKGROUND: Recurrent wheezing during infancy is a heterogeneous disorder that has
been associated with early-onset asthma. OBJECTIVE: To identify phenotypes of severe …

The short-term benefits of breast-feeding are well-established and include a reduced risk of
gastroenteritis, ear infection and atopy during infancy. More recently, there has been …

Breastmilk has many documented beneficial effects on the developing human infant, but the
components of breastmilk that influence these developmental pathways have not been fully …