The interplay between inflammatory pathways and COVID-19: A critical review on pathogenesis and therapeutic options
S Choudhary, K Sharma, O Silakari - Microbial pathogenesis, 2021 - Elsevier
Abstract COVID-19, caused by SARS-CoV-2, emerged as the deadliest outbreak that has
now become a serious health issue to mankind. Activation of inflammatory signaling …
now become a serious health issue to mankind. Activation of inflammatory signaling …
Association between tumor necrosis factor inhibitors and the risk of hospitalization or death among patients with immune-mediated inflammatory disease and COVID …
Importance Although tumor necrosis factor (TNF) inhibitors are widely prescribed globally
because of their ability to ameliorate shared immune pathways across immune-mediated …
because of their ability to ameliorate shared immune pathways across immune-mediated …
SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication
Abstract The recently identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) is the cause of the COVID-19 pandemic. How this novel beta-coronavirus virus, and …
CoV-2) is the cause of the COVID-19 pandemic. How this novel beta-coronavirus virus, and …
A review on currently available potential therapeutic options for COVID-19
S Ohadian Moghadam - International Journal of General Medicine, 2020 - Taylor & Francis
A series of unexplained pneumonia cases currently were first reported in December 2019 in
Wuhan, China. Official names have been announced for the virus responsible, previously …
Wuhan, China. Official names have been announced for the virus responsible, previously …
Weighted gene co-expression network analysis combined with machine learning validation to identify key modules and hub genes associated with SARS-CoV-2 …
The coronavirus disease-2019 (COVID-19) pandemic has caused an enormous loss of lives.
Various clinical trials of vaccines and drugs are being conducted worldwide; nevertheless …
Various clinical trials of vaccines and drugs are being conducted worldwide; nevertheless …
The Persian COVID stress scales (Persian-CSS) and COVID-19-related stress reactions in patients with obsessive-compulsive and anxiety disorders
V Khosravani, GJG Asmundson, S Taylor… - Journal of obsessive …, 2021 - Elsevier
Abstract The COVID Stress Scales (CSS) were designed to assess stress related to the
COVID-19 pandemic. Emerging evidence indicates that people with anxiety disorders (ADs) …
COVID-19 pandemic. Emerging evidence indicates that people with anxiety disorders (ADs) …
[HTML][HTML] Identification of multipotent drugs for COVID-19 therapeutics with the evaluation of their SARS-CoV2 inhibitory activity
The SARS-CoV2 is a highly contagious pathogen that causes COVID-19 disease. It has
affected millions of people globally with an average lethality of~ 3%. There is an urgent need …
affected millions of people globally with an average lethality of~ 3%. There is an urgent need …
The folate antagonist methotrexate diminishes replication of the coronavirus SARS-CoV-2 and enhances the antiviral efficacy of remdesivir in cell culture models
KM Stegmann, A Dickmanns, S Gerber, V Nikolova… - Virus research, 2021 - Elsevier
The search for successful therapies of infections with the coronavirus SARS-CoV-2 is
ongoing. We tested inhibition of host cell nucleotide synthesis as a promising strategy to …
ongoing. We tested inhibition of host cell nucleotide synthesis as a promising strategy to …
[HTML][HTML] TNF-α blockers showed prophylactic effects in preventing COVID-19 in patients with rheumatoid arthritis and seronegative spondyloarthropathies: a case …
M Salesi, B Shojaie, Z Farajzadegan, N Salesi… - Rheumatology and …, 2021 - Springer
Methods A case–control study was conducted through interviews based on a structured
questionnaire to investigate the frequency of COVID-19 incidence in 254 eligible patients …
questionnaire to investigate the frequency of COVID-19 incidence in 254 eligible patients …
Detecting the multiomics signatures of factor-specific inflammatory effects on airway smooth muscles
Smooth muscles are a specific muscle subtype that is widely identified in the tissues of
internal passageways. This muscle subtype has the capacity for controlled or regulated …
internal passageways. This muscle subtype has the capacity for controlled or regulated …