[HTML][HTML] Macrophages as a therapeutic target to promote diabetic wound healing

M Sharifiaghdam, E Shaabani, R Faridi-Majidi… - Molecular Therapy, 2022 - cell.com
It is well‏‏ established that macrophages are key regulators of wound healing, displaying
impressive plasticity and an evolving phenotype, from an aggressive pro-inflammatory or" …

Physical activity for cognitive health promotion: an overview of the underlying neurobiological mechanisms

C Chen, S Nakagawa - Ageing research reviews, 2023 - Elsevier
Physical activity is one of the modifiable factors of cognitive decline and dementia with the
strongest evidence. Although many influential reviews have illustrated the neurobiological …

[HTML][HTML] Redefining chronic inflammation in aging and age-related diseases: proposal of the senoinflammation concept

HY Chung, DH Kim, EK Lee, KW Chung… - Aging and …, 2019 - ncbi.nlm.nih.gov
Age-associated chronic inflammation is characterized by unresolved and uncontrolled
inflammation with multivariable low-grade, chronic and systemic responses that exacerbate …

Geriatric traumatic brain injury: epidemiology, outcomes, knowledge gaps, and future directions

RC Gardner, K Dams-O'Connor… - Journal of …, 2018 - liebertpub.com
This review of the literature on traumatic brain injury (TBI) in older adults focuses on incident
TBI sustained in older adulthood (“geriatric TBI”) rather than on the separate, but related …

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

T Tchkonia, Y Zhu, J Van Deursen… - The Journal of …, 2013 - Am Soc Clin Investig
Aging is the largest risk factor for most chronic diseases, which account for the majority of
morbidity and health care expenditures in developed nations. New findings suggest that …

Salivary biomarkers: novel noninvasive tools to diagnose chronic inflammation

P Dongiovanni, M Meroni, S Casati, R Goldoni… - International journal of …, 2023 - nature.com
Several chronic disorders including type 2 diabetes (T2D), obesity, heart disease and
cancer are preceded by a state of chronic low-grade inflammation. Biomarkers for the early …

Satellite cells in human skeletal muscle plasticity

T Snijders, JP Nederveen, BR McKay… - Frontiers in …, 2015 - frontiersin.org
Skeletal muscle satellite cells are considered to play a crucial role in muscle fiber
maintenance, repair and remodeling. Our knowledge of the role of satellite cells in muscle …

Ageing and the telomere connection: An intimate relationship with inflammation

J Zhang, G Rane, X Dai, MK Shanmugam… - Ageing research …, 2016 - Elsevier
Telomeres are the heterochromatic repeat regions at the ends of eukaryotic chromosomes,
whose length is considered to be a determinant of biological ageing. Normal ageing itself is …

Visceral Adiposity Index: a reliable indicator of visceral fat function associated with cardiometabolic risk

MC Amato, C Giordano, M Galia, A Criscimanna… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE To individuate a novel sex-specific index, based on waist circumference, BMI,
triglycerides, and HDL cholesterol, indirectly expressing visceral fat function. RESEARCH …

[HTML][HTML] Muscle as an endocrine organ: focus on muscle-derived interleukin-6

BK Pedersen, MA Febbraio - Physiological reviews, 2008 - journals.physiology.org
Skeletal muscle has recently been identified as an endocrine organ. It has, therefore, been
suggested that cytokines and other peptides that are produced, expressed, and released by …