Silymarin as supportive treatment in liver diseases: a narrative review

A Gillessen, HHJ Schmidt - Advances in therapy, 2020 - Springer
Silymarin, an extract from milk thistle seeds, has been used for centuries to treat hepatic
conditions. Preclinical data indicate that silymarin can reduce oxidative stress and …

[HTML][HTML] Oxidative stress as a crucial factor in liver diseases

H Cichoż-Lach, A Michalak - World journal of gastroenterology …, 2014 - ncbi.nlm.nih.gov
Redox state constitutes an important background of numerous liver disorders. The redox
state participates in the course of inflammatory, metabolic and proliferative liver diseases …

[HTML][HTML] Beneficial effects of naringenin in liver diseases: Molecular mechanisms

E Hernández-Aquino, P Muriel - World journal of gastroenterology, 2018 - ncbi.nlm.nih.gov
Liver diseases are caused by different etiological agents, mainly alcohol consumption,
viruses, drug intoxication or malnutrition. Frequently, liver diseases are initiated by oxidative …

Insights into the role and interdependence of oxidative stress and inflammation in liver diseases

S Li, M Hong, HY Tan, N Wang… - Oxidative medicine and …, 2016 - Wiley Online Library
The crucial roles of oxidative stress and inflammation in the development of hepatic
diseases have been unraveled and emphasized for decades. From steatosis to fibrosis …

Role of oxidative stress and molecular changes in liver fibrosis: a review

V Sánchez-Valle, NC Chavez-Tapia… - Current medicinal …, 2012 - ingentaconnect.com
Liver fibrosis represents a health problem with significant morbidity and mortality that affects
100 million people worldwide. It is a final pathway to several chronic liver diseases and is …

HBx facilitates ferroptosis in acute liver failure via EZH2 mediated SLC7A11 suppression

GZ Liu, XW Xu, SH Tao, MJ Gao, ZH Hou - Journal of biomedical science, 2021 - Springer
Background Acute liver failure (ALF) is a syndrome of severe hepatocyte injury with high rate
of mortality. Hepatitis B virus (HBV) infection is the major cause of ALF worldwide, however …

Implications of oxidative stress on viral pathogenesis

FC Camini, CC da Silva Caetano, LT Almeida… - Archives of …, 2017 - Springer
Reactive species are frequently formed after viral infections. Antioxidant defences, including
enzymatic and non-enzymatic components, protect against reactive species, but sometimes …

[HTML][HTML] Fructose as a key player in the development of fatty liver disease

M Basaranoglu, G Basaranoglu… - World journal of …, 2013 - ncbi.nlm.nih.gov
We aimed to investigate whether increased consumption of fructose is linked to the
increased prevalence of fatty liver. The prevalence of nonalcoholic steatohepatitis (NASH) is …

Oxidative stress and liver cancer: etiology and therapeutic targets

Z Wang, Z Li, Y Ye, L Xie, W Li - Oxidative medicine and …, 2016 - Wiley Online Library
Accumulating evidence has indicated that oxidative stress (OS) is associated with the
development of hepatocellular carcinoma (HCC). However, the mechanisms remain largely …

[HTML][HTML] Molecular mechanism of hepatitis B virus-induced hepatocarcinogenesis

M Tarocchi, S Polvani, G Marroncini… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) infection is a global public health problem with approximately 2
billion people that have been exposed to the virus. HBV is a member of a family of small …