HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression
B Keith, RS Johnson, MC Simon - Nature Reviews Cancer, 2012 - nature.com
Hypoxia-inducible factors (HIFs) are broadly expressed in human cancers, and HIF1α and
HIF2α were previously suspected to promote tumour progression through largely …
HIF2α were previously suspected to promote tumour progression through largely …
[HTML][HTML] Adverse outcome pathway from activation of the AhR to breast cancer-related death
L Benoit, F Jornod, E Zgheib, C Tomkiewicz… - Environment …, 2022 - Elsevier
Adverse outcome pathways (AOPs) are formalized and structured linear concepts that
connect one molecular initiating event (MIE) to an adverse outcome (AO) via different key …
connect one molecular initiating event (MIE) to an adverse outcome (AO) via different key …
13C NMR-Based Metabolomics for the Classification of Green Coffee Beans According to Variety and Origin
F Wei, K Furihata, M Koda, F Hu, R Kato… - Journal of Agricultural …, 2012 - ACS Publications
13C NMR-based metabolomics was demonstrated as a useful tool for distinguishing the
species and origins of green coffee bean samples of arabica and robusta from six different …
species and origins of green coffee bean samples of arabica and robusta from six different …
Hypoxia-inducible aryl hydrocarbon receptor nuclear translocator (ARNT)(HIF-1β): is it a rare exception?
M Mandl, R Depping - Molecular Medicine, 2014 - Springer
The aryl hydrocarbon receptor nuclear translocator (ARNT), also designated as hypoxia-
inducible factor (HIF)-1β, plays a pivotal role in the adaptive responses to (micro-) …
inducible factor (HIF)-1β, plays a pivotal role in the adaptive responses to (micro-) …
Non-viral nanocarriers for siRNA delivery in breast cancer
Breast cancer is the most frequently diagnosed malignancy in American women. While
significant progress has been made in the development of modern diagnostic tools and …
significant progress has been made in the development of modern diagnostic tools and …
[HTML][HTML] siRNA-based nanocarriers for targeted drug delivery to control breast cancer
Breast cancer is a challenging health issue in women and the second-leading cause of
mortality around world. In this review, we addressed beneficial role of siRNA to control …
mortality around world. In this review, we addressed beneficial role of siRNA to control …
Application of genomics, proteomics and metabolomics in drug discovery, development and clinic
Genomics, proteomics and metabolomics are three areas that are routinely applied
throughout the drug-development process as well as after a product enters the market. This …
throughout the drug-development process as well as after a product enters the market. This …
Downregulation of ARNT2 promotes tumor growth and predicts poor prognosis in human hepatocellular carcinoma
W Li, Y Liang, B Yang, H Sun… - … of gastroenterology and …, 2015 - Wiley Online Library
Abstract Background and Aim Aryl‐hydrocarbon receptor nuclear translocator 2 (ARNT2) is
a transcriptional regulator and member of the basic helix‐loop‐helix/P er‐ARNT‐SIM …
a transcriptional regulator and member of the basic helix‐loop‐helix/P er‐ARNT‐SIM …
Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness
A Bogeas, G Morvan-Dubois, EA El-Habr… - Acta …, 2018 - Springer
Although a growing body of evidence indicates that phenotypic plasticity exhibited by
glioblastoma cells plays a central role in tumor development and post-therapy recurrence …
glioblastoma cells plays a central role in tumor development and post-therapy recurrence …
ARNT2 is downregulated and serves as a potential tumor suppressor gene in non-small cell lung cancer
B Yang, E Yang, H Liao, Z Wang, Z Den, H Ren - Tumor Biology, 2015 - Springer
The present study aims to investigate the expression pattern of aryl hydrocarbon receptor
nuclear translocator 2 (ARNT2) protein and its clinical significance in human non-small cell …
nuclear translocator 2 (ARNT2) protein and its clinical significance in human non-small cell …