Mesenchymal stem cells for spinal cord injury: current options, limitations, and future of cell therapy
Spinal cord injury (SCI) constitutes an inestimable public health issue. The most crucial
phase in the pathophysiological process of SCI concerns the well-known secondary injury …
phase in the pathophysiological process of SCI concerns the well-known secondary injury …
Dental pulp stem cell-derived secretome and its regenerative potential
JK Bar, A Lis-Nawara, PG Grelewski - International journal of molecular …, 2021 - mdpi.com
The therapeutic potential of the dental pulp stem (DSC) cell-derived secretome, consisting of
various biomolecules, is undergoing intense research. Despite promising in vitro and in vivo …
various biomolecules, is undergoing intense research. Despite promising in vitro and in vivo …
Extracellular vesicles derived from human Wharton's jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced …
V Bodart-Santos, LRP de Carvalho… - Stem cell research & …, 2019 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have been explored as promising
tools for treatment of several neurological and neurodegenerative diseases. MSCs release …
tools for treatment of several neurological and neurodegenerative diseases. MSCs release …
[HTML][HTML] Mesenchymal stromal cell secretome for traumatic brain injury: Focus on immunomodulatory action
F Pischiutta, E Caruso, H Cavaleiro, AJ Salgado… - Experimental …, 2022 - Elsevier
The severity and long-term consequences of brain damage in traumatic brain injured (TBI)
patients urgently calls for better neuroprotective/neuroreparative strategies for this …
patients urgently calls for better neuroprotective/neuroreparative strategies for this …
Paracrine effects of mesenchymal stem cells in ischemic stroke: Opportunities and challenges
It is well acknowledged that neuroprotective effects of transplanted mesenchymal stem cells
(MSCs) in ischemic stroke are attributed to their paracrine-mediated actions or bystander …
(MSCs) in ischemic stroke are attributed to their paracrine-mediated actions or bystander …
Therapeutic potential of astrocyte transplantation
N Hastings, WL Kuan, A Osborne… - Cell …, 2022 - journals.sagepub.com
Cell transplantation is an attractive treatment strategy for a variety of brain disorders, as it
promises to replenish lost functions and rejuvenate the brain. In particular, transplantation of …
promises to replenish lost functions and rejuvenate the brain. In particular, transplantation of …
Conditioned medium from induced pluripotent stem cell-derived mesenchymal stem cells accelerates cutaneous wound healing through enhanced angiogenesis
X Liang, F Lin, Y Ding, Y Zhang, M Li, X Zhou… - Stem cell research & …, 2021 - Springer
Abstract Background Mesenchymal stem cells (MSCs) can improve cutaneous wound
healing via the secretion of growth factors. However, the therapeutic efficacy of MSCs varies …
healing via the secretion of growth factors. However, the therapeutic efficacy of MSCs varies …
KIAA1199 deficiency enhances skeletal stem cell differentiation to osteoblasts and promotes bone regeneration
Upon transplantation, skeletal stem cells (also known as bone marrow stromal or
mesenchymal stem cells) can regulate bone regeneration by producing secreted factors …
mesenchymal stem cells) can regulate bone regeneration by producing secreted factors …
Combined cell-based therapy strategies for the treatment of Parkinson's disease: focus on mesenchymal stromal cells
J Rodríguez-Pallares, M García-Garrote… - Neural Regeneration …, 2023 - journals.lww.com
Parkinson's disease is a neurodegenerative condition characterized by motor impairments
caused by the selective loss of dopaminergic neurons in the substantia nigra. Levodopa is …
caused by the selective loss of dopaminergic neurons in the substantia nigra. Levodopa is …
Secretome as a Tool to Treat Neurological Conditions: Are We Ready?
AV da Silva, I Serrenho, B Araújo, AM Carvalho… - International Journal of …, 2023 - mdpi.com
Due to their characteristics, mesenchymal stem cells (MSCs) are considered a potential
therapy for brain tissue injury or degeneration. Nevertheless, despite the promising results …
therapy for brain tissue injury or degeneration. Nevertheless, despite the promising results …