Natural compounds targeting nuclear receptors for effective cancer therapy

M Hegde, S Girisa, N Naliyadhara, A Kumar… - Cancer and Metastasis …, 2023 - Springer
Human nuclear receptors (NRs) are a family of forty-eight transcription factors that modulate
gene expression both spatially and temporally. Numerous biochemical, physiological, and …

Oral delivery of curcumin via multi-bioresponsive polyvinyl alcohol and guar gum based double-membrane microgels for ulcerative colitis therapy

Y Hu, S Zhang, Z Wen, H Fu, J Hu, X Ye, L Kang… - International Journal of …, 2022 - Elsevier
Anti-inflammatory drugs for ulcerative colitis (UC) treatment should specifically penetrate
and accumulate in the colon tissue. Herein, a multi-bioresponsive anti-inflammatory drug …

[HTML][HTML] Anticancer plant-derivatives: Deciphering their oncopreventive and therapeutic potential in molecular terms

R Gahtori, AH Tripathi, A Kumari, N Negi… - Future Journal of …, 2023 - Springer
Background Over the years, phytomedicines have been widely used as natural modalities
for the treatment and prevention of various diseases by different ethnic groups across the …

[HTML][HTML] Advances in RNAi therapies for gastric cancer: Targeting drug resistance and nanoscale delivery

M Hashemi, R Aparviz, M Beickzade… - Biomedicine & …, 2023 - Elsevier
Gastric cancer poses a significant health challenge, and exploring innovative therapeutic
strategies is imperative. RNA interference (RNAi) has employed as an important therapeutic …

[HTML][HTML] Thermal-and radiation-sensitive hydrogel based on hydroxyethyl cellulose and manganese dioxide nanoparticles for synergistic chemoradiotherapy of breast …

S Zare, M Eskandani, H Derakhshankhah… - Carbohydrate Polymer …, 2023 - Elsevier
A thermal-and radiation-sensitive nanocomposite hydrogel-based drug delivery system
(DDS) composed of hydroxyethyl cellulose (HEC), poly (N-isopropylacrylamide)(PNIPAAm) …

[HTML][HTML] Withaferin A: A Pleiotropic Anticancer Agent from the Indian Medicinal Plant Withania somnifera (L.) Dunal

S Kumar, SO Mathew, RP Aharwal, HS Tulli… - Pharmaceuticals, 2023 - mdpi.com
Cancer represents the second most deadly disease and one of the most important public
health concerns worldwide. Surgery, chemotherapy, radiation therapy, and immune therapy …

[HTML][HTML] Targeting cancer stem cells by dietary agents: an important therapeutic strategy against human malignancies

M Deldar Abad Paskeh, S Asadi, A Zabolian… - International Journal of …, 2021 - mdpi.com
As a multifactorial disease, treatment of cancer depends on understanding unique
mechanisms involved in its progression. The cancer stem cells (CSCs) are responsible for …

[HTML][HTML] Advanced application of nanotechnology in active constituents of Traditional Chinese Medicines

C Qiu, JZ Zhang, B Wu, CC Xu, HH Pang… - Journal of …, 2023 - Springer
Abstract Traditional Chinese Medicines (TCMs) have been used for centuries for the
treatment and management of various diseases. However, their effective delivery to targeted …

Involvement of microRNA modifications in anticancer effects of major polyphenols from green tea, coffee, wine, and curry

T Ohishi, S Hayakawa, N Miyoshi - Critical Reviews in Food …, 2023 - Taylor & Francis
Epidemiological studies have shown that consumption of green tea, coffee, wine, and curry
may contribute to a reduced risk of various cancers. However, there are some cancer site …

Current appraises of therapeutic applications of nanocurcumin: A novel drug delivery approach for biomaterials in dentistry

RA Bapat, SV Bedia, AS Bedia, HJ Yang… - Environmental …, 2023 - Elsevier
Curcumin is a natural herb and polyphenol that is obtained from the medicinal plant
Curcuma longa. It's anti-bacterial, anti-inflammatory, anti-cancer, anti-mutagenic, antioxidant …