[HTML][HTML] Pharmaceutical resource discovery from traditional medicinal plants: Pharmacophylogeny and pharmacophylogenomics

D Hao, P Xiao - Chinese Herbal Medicines, 2020 - Elsevier
The worldwide botanical and medicinal culture diversity are astonishing and constitute a
Pierian spring for innovative drug R&D. Here, the latest awareness and the perspectives of …

Potential anticoagulant of traditional Chinese medicine and novel targets for anticoagulant drugs

Q Yin, X Zhang, S Liao, X Huang, CC Wan, Y Wang - Phytomedicine, 2023 - Elsevier
Background Anticoagulants are the main drugs used for the prevention and treatment of
thrombosis. Currently, anticoagulant drugs are primarily multitarget heparin drugs, single …

[HTML][HTML] Nutraceuticals for peripheral vestibular pathology: properties, usefulness, future perspectives and medico-legal aspects

G Chiarella, G Marcianò, P Viola, C Palleria, D Pisani… - Nutrients, 2021 - mdpi.com
Vestibular disorders may generate complex signs and symptoms, which may alter patients'
balance and the quality of life. Dizziness and vertigo can strongly affect daily activities and …

[HTML][HTML] Molecular mechanism of tanshinone against prostate cancer

W Li, T Huang, S Xu, B Che, Y Yu, W Zhang, K Tang - Molecules, 2022 - mdpi.com
Prostate cancer (PCa) is the most common malignant tumor of the male urinary system in
Europe and America. According to the data in the World Cancer Report 2020, the incidence …

[HTML][HTML] The biology of medicinal resource substitution in Salvia

N Cui, T Chen, B Liao, J Xu, X Li - Chinese Medicine, 2021 - Springer
Background The decrease of wild reserves and the sharp increase of market demand have
led to resource substitution, but it is still not clear how to discover medicinal alternative …

Impact of drug metabolism/pharmacokinetics and their relevance upon traditional medicine-based cardiovascular drug research

DC Hao, PG Xiao - Current Drug Metabolism, 2019 - ingentaconnect.com
Background: The representative cardiovascular herbs, ie Panax, Ligusticum, Carthamus,
and Pueraria plants, are traditionally and globally used in the prevention and treatment of …

Salvia miltiorrhiza Resources, Cultivation, and Breeding

C Sui - The Salvia miltiorrhiza Genome, 2019 - Springer
Salvia miltiorrhiza Bunge is the source species of Danshen listed in Chinese
Pharmacopoeia (2015 edition). Currently, the germplasm of S. miltiorrhiza and its related …

Plant pharmacophylogeny: past, present and future.

D Hao, P Xiao - Journal of Chinese Pharmaceutical …, 2020 - search.ebscohost.com
The concept of" pharmacophylogeny" was proposed by Peigen Xiao in the 1980s based on
long-term studies of Chinese researchers since ancient times and especially the 1950s. The …

Effect of oridonin on cytochrome P450 expression and activities in HepaRG cell

Y Zhang, X Zheng, Y Liu, L Fang, Z Pan, M Bao… - Pharmacology, 2018 - karger.com
Oridonin, the major terpene found in Rabdosia rubescens, is widely used as a dietary
supplement or therapeutic drug. However, the effects of oridonin on major CYP450s are still …

Induced Autotetraploids in Salvia miltiorrhiza and Their Agronomic Traits

S Ma, C Sun, W Su, L Zhang, J Zheng, S Su, W Zhao… - Cytologia, 2023 - jstage.jst.go.jp
Salvia miltiorrhiza is an important medicinal plant for its special pharmacological activity in
cardiovascular and cerebrovascular diseases. The objective of this work was to develop S …