Significant recent progress in understanding rheumatoid arthritis (RA) pathogenesis has led
to improved treatment and quality of life. The introduction of targeted-biologic and-synthetic …

The vagus nerve is an indispensable body-brain connection that controls vital aspects of
autonomic physiology like breathing, heart rate, blood pressure, and gut motility, reflexes …

Increasing evidence indicates that the brain regulates peripheral immunity, yet whether and
how the brain represents the state of the immune system remains unclear. Here, we show …

The neuroanatomical basis behind acupuncture practice is still poorly understood. Here, we
used intersectional genetic strategy to ablate NPY+ noradrenergic neurons and/or adrenal …

Depression and obesity are common conditions with major public health implications that
tend to co-occur within individuals. The relationship between these conditions is …

Trauma can affect any individual at any location and at any time over a lifespan. The
disruption of macrobarriers and microbarriers induces instant activation of innate immunity …

Sensory functions of the vagus nerve are critical for conscious perceptions and for
monitoring visceral functions in the cardio-pulmonary and gastrointestinal systems. Here, we …

Active research at the frontiers of immunology and neuroscience has identified multiple
points of interaction and communication between the immune system and the nervous …

Neuroinflammation has become a key hallmark of neurological complications including
perioperative pathologies such as postoperative delirium and longer-lasting postoperative …

The nervous system regulates immunity and inflammation. The molecular detection of
pathogen fragments, cytokines, and other immune molecules by sensory neurons generates …