Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) belongs to polyphenols' stilbenoids group,
possessing two phenol rings linked to each other by an ethylene bridge. This natural …

Proliferation is an important part of cancer development and progression. This is manifest by
altered expression and/or activity of cell cycle related proteins. Constitutive activation of …

Resveratrol is mainly found in grapes and red wine, also in some plants and fruits, such as
peanuts, cranberries, pistachios, blueberries and bilberries. Moreover, nowadays this …

Cyclin D1 is an important regulator of cell cycle progression and can function as a
transcriptionl co-regulator. The overexpression of cyclin D1 has been linked to the …

Resveratrol (3, 4′, 5-trihydroxystilbene) is found in various plants, including grapes, berries
and peanuts. It is also present in wines, especially red wines. During the last years, it has …

A plant kingdom is considered as a gold mine for the discovery of many biologically active
substances with therapeutic values. Resveratrol (3, 5, 4′-trihydroxystilbene), a naturally …

Abstract Sirtuins (SIRTs 1− 7), or class III histone deacetylases (HDACs), are protein
deacetylases/ADP ribosyltransferases that target a wide range of cellular proteins in the …

SIRT1 is a multifaceted, NAD+-dependent protein deacetylase that is involved in a wide
variety of cellular processes from cancer to ageing. The function of SIRT1 in cancer is …

Vascular endothelial growth factor receptor-2 (VEGFR-2) plays a critical role in cancer
angiogenesis. Inhibition of VEGFR-2 activity proved effective suppression of tumour …

Resveratrol, an antioxidant polyphenol from red wine, has been the subject of intense
interest in recent years due to a range of unique anti‐aging properties. These include …