Endothelial dysfunction is characterized by a reduction in nitric oxide generation or an
unbalanced distribution of the relaxing and contracting pressures produced by endothelial …

Liposomes are sphere-shaped vesicles that can capture therapeutics either in the outer
phospholipid bilayer or inner aqueous core. Liposomes, especially when surface-modified …

Multifunctional fatty acid grafted polymeric micelles are an effective and promising approach
for drug and gene delivery to the brain. An alternative approach to bypass the blood–brain …

This narrative review provides an overview of the current advances, challenges, and
opportunities in nanoparticle drug delivery for central nervous system (CNS) disorders. The …

Polymeric nanoparticle drug delivery systems are increasingly viewed as crucial building
blocks for efficacious treatments of disease conditions. However, production methods at …

Objective Non-tricyclic antidepressants (non-TCAs) work by preventing the intake of
norepinephrine and serotonin. Therefore, the aim of this study was to identify a potent non …

Chitosan-based polymeric micelles are promising non-viral nanocarriers for safe and
targeted gene delivery. Multi-functionalized chitosan polymeric micelles were prepared by …

This study aimed to deliver a potential water-soluble antiviral drug (sofosbuvir) through
optimized vesicular lipid nanocarriers (LNs) to the rat brain as a novel strategy against viral …

Abstract Nanoparticles (NPs) with 'stealth'properties have been designed to decrease the
phagocytosis of such particles by mononuclear phagocytes and to protect them from …

Background: Borneol can enhance the blood-brain barrier (BBB) permeability of some drugs
and suppress the efflux transport of P-glycoprotein (P-gp), which will contribute to the brain …