Calcific aortic valve disease (CAVD) is the most common disorder affecting heart valves and
is characterized by thickening, fibrosis and mineralization of the aortic valve leaflets …

Glycosaminoglycans (GAGs) are complex polysaccharides exhibiting a vast structural
diversity and fulfilling various functions mediated by thousands of interactions in the …

Glycosaminoglycans (GAGs) are abundant, ubiquitous carbohydrates in biology, yet their
structural complexity has limited an understanding of their biological roles and structure …

Glycosaminoglycans (GAGs) play a crucial role in tissue homeostasis by regulating the
activity and diffusion of bioactive molecules. Incorporating GAGs into biomaterials has …

Abstract Platelet factor 4 (PF4) combines with heparin to form an antigen that could produce
IgG antibodies and participate in heparin-induced thrombocytopenia (HIT). PF4 has …

In this study, a purified macromolecular sulfate glycosaminoglycan whose structural
characterization is similar to chondroitin sulfate from the swim bladder of Aristichthys nobilis …

Mammalian glycosaminoglycans (GAGs), except hyaluronan (HA), are sulfated
polysaccharides that are covalently attached to core proteins to form proteoglycans (PGs) …

In this comprehensive review, we will dissect the impact of research on proteoglycans
focusing on recent developments involved in their synthesis, degradation, and interactions …

Syndecans are transmembrane heparan sulfate proteoglycans present on most mammalian
cell surfaces. They have a long evolutionary history, a single syndecan gene being …

This review examines the roles of HS–proteoglycans (HS–PGs) in general, and, in
particular, perlecan and syndecan as representative examples and their interactive ligands …