Fate and impact of nanoplastics in the human digestive environment after oral exposure: A common challenge for toxicology and chemistry

C Liebgott, I Chaib, P Doyen, H Robert… - TrAC Trends in …, 2023 - Elsevier
Nanoplastics (NPLs), the presence in the environment of which was considered only “highly
plausible” until recently, have become the focus of environmental and ecotoxicological …

The impact of air pollution on the course of cystic fibrosis: a review

M Blayac, P Coll, V Urbach, P Fanen, R Epaud… - Frontiers in …, 2022 - frontiersin.org
Cystic fibrosis (CF) is a lethal and widespread autosomal recessive disorder affecting over
80,000 people worldwide. It is caused by mutations of the CFTR gene, which encodes an …

[HTML][HTML] Human risk associated with exposure to mixtures of antiandrogenic chemicals evaluated using in vitro hazard and human biomonitoring data

Y Ma, C Taxvig, A Rodríguez-Carrillo, V Mustieles… - Environment …, 2023 - Elsevier
Background Scientific evidence for underestimated toxicity from unintentional exposure to
chemical mixtures is mounting. Yet, harmonized approaches on how to assess the actual …

Role of Artificial Intelligence in Multinomial Decisions and Preventative Nutrition in Alzheimer's Disease

A Soares Dias Portela, V Saxena… - Molecular Nutrition & …, 2024 - Wiley Online Library
Alzheimer's disease (AD) affects 50 million people worldwide, an increase of 35 million
since 2015, and it is known for memory loss and cognitive decline. Considering the …

Infectious Diseases Associated with Exposure to Pollutants in a Local Population from Mexico

A Mauricio-Gutiérrez, O Romero-Arenas… - Applied Sciences, 2023 - mdpi.com
Agriculture is one of the primary activities in the municipality of Acatzingo, Puebla, Mexico.
Agricultural fields are affected by the indiscriminate use of pesticides and hydrocarbon spills …

Exposome and chemists

BL Milman, IК Zhurkovich - Analitika, 2023 - journals.eco-vector.com
This article is an overview description of exposomics that is a concept and a modern field of
biomedical and chemical-analytical research related to the study of the integrity of various …

Pomotrelvir and Nirmatrelvir Binding and Reactivity with SARS‐CoV‐2 Main Protease: Implications for Resistance Mechanisms from Computations

I Tunón, J Schillings, CA Ramos-Guzmán… - Angewandte Chemie … - Wiley Online Library
We investigate the inhibition mechanism between pomotrelvir and the SARS‐CoV‐2 main
protease using molecular mechanics and quantum mechanics/molecular mechanics …

A Computational Comparison Between Pomotrelvir and Nirmatrelvir Binding and Reactivity with SARS-CoV-2 Main Protease. Implications for Resistance Mechanisms

J Schillings, CA Ramos-Guzmán, JJ Ruiz-Pernía… - 2024 - chemrxiv.org
This study investigates the binding mode and reaction mechanism between pomotrelvir and
the SARS-CoV-2 main protease using a combination of molecular mechanics and hybrid …