Vaccines and monoclonal antibodies: new tools for malaria control

K Miura, Y Flores-Garcia, CA Long… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Malaria remains one of the biggest health problems in the world. While significant reductions
in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend …

The Need for Novel Asexual Blood-Stage Malaria Vaccine Candidates for Plasmodium falciparum

E Takashima, H Otsuki, M Morita, D Ito, H Nagaoka… - Biomolecules, 2024 - mdpi.com
Extensive control efforts have significantly reduced malaria cases and deaths over the past
two decades, but in recent years, coupled with the COVID-19 pandemic, success has …

Plasmodium falciparum merozoite surface protein 1 as asexual blood stage malaria vaccine candidate

R Thomson-Luque, TC Stabler, K Fürle… - Expert Review of …, 2024 - Taylor & Francis
Introduction Malaria represents a public health challenge in tropical and subtropical regions,
and currently deployed control strategies are likely insufficient to drive elimination of malaria …

Full-length MSP1 is a major target of protective immunity after controlled human malaria infection

M Rosenkranz, IN Nkumama, R Ogwang… - Life science …, 2024 - life-science-alliance.org
The merozoite surface protein 1 (MSP1) is the most abundant protein on the surface of the
invasive merozoite stages of Plasmodium falciparum and has long been considered a key …

[HTML][HTML] The fentanyl-specific antibody FenAb024 can shield against carfentanil effects

K Urban, A Gkeka, M Chandra, D Greiner, S Pollich… - Toxicology Letters, 2024 - Elsevier
The surge in opioid-related deaths, driven predominantly by fentanyl and its synthetic
derivatives, has become a critical public health concern, which is particularly evident in the …

IgG Subclass Switch in Volunteers Repeatedly Immunized with the Full-Length Plasmodium falciparum Merozoite Surface Protein 1 (MSP1)

V Rathay, K Fürle, V Kiehl, A Ulmer, M Lanzer… - Vaccines, 2024 - mdpi.com
Vaccines are highly effective tools against infectious diseases and are also considered
necessary in the fight against malaria. Vaccine-induced immunity is frequently mediated by …