Alzheimer and Parkinson diseases, frontotemporal lobar degeneration and amyotrophic lateral sclerosis overlapping neuropathology start in the first two decades of …

L Calderón-Garcidueñas, EW Stommel… - Frontiers in Human …, 2024 - frontiersin.org
The neuropathological hallmarks of Alzheimer's disease (AD), Parkinson's disease (PD),
frontotemporal lobar degeneration (FTLD), and amyotrophic lateral sclerosis (ALS) are …

Frontotemporal Dementia Subtyping using Machine Learning, Multivariate Statistics, and Neuroimaging

A Metz, Y Zeighami, S Ducharme, S Villeneuve… - medRxiv, 2024 - medrxiv.org
Frontotemporal Dementia (FTD) is a prevalent form of early-onset dementia characterized by
progressive neurodegeneration. It encompasses a group of heterogeneous disorders …

Longitudinal deformation based morphometry pipeline to study neuroanatomical differences in structural MRI based on SyN unbiased templates

J Germann, F Venetucci Gouveia, MM Chakravarty… - bioRxiv, 2024 - biorxiv.org
Morphometric measures in humans derived from magnetic resonance imaging (MRI) have
provided important insights into brain differences and changes associated with development …

Joint signatures of morphological and microstructural inter-individual variation in the Alzheimer's spectrum

A Bussy, R Patel, O Parent, A Salaciak, SA Bedford… - bioRxiv, 2024 - biorxiv.org
Alzheimer's disease (AD) is primarily characterized by the accumulation of amyloid and tau
pathologies. However, alterations in the detailed organization and composition of neural …

Investigation of the hippocampus in aging and Alzheimer's disease progression using multimodal MRI techniques

A Bussy - 2023 - escholarship.mcgill.ca
Across the globe, most nations are facing challenges posed by longer life expectancy
resulting in the increased proportion of elderly citizens and prevalence of …