Simple Summary Tumor cells from the same specimen are functionally heterogeneous.
Cancer stem cells (CSCs) are populations of tumor cells with self-renewal and differentiation …

The key role of cancer stem cells (CSCs) in tumor development and therapy resistance
makes them essential biomarkers and therapeutic targets. Numerous agents targeting …

Human exposure to low-to-moderate dose ionizing radiation (LMD-IR) is increasing via
environmental, medical, occupational sources. Acute exposure to LMD-IR can cause …

Simple Summary Radiotherapy is one of the most common treatments for cancer.
Overcoming the failure and side effects of radiotherapy are current challenges. It has been …

Simple Summary Cells with stem-like potential in head and neck squamous cell carcinoma
(HNSCC) have been shown to exhibit features of intrinsic resistance to ionizing radiation …

Radiotherapy plays an essential role in the treatment of head and neck squamous cell
carcinoma (HNSCC), yet radioresistance remains a major barrier to therapeutic efficacy. A …

The release and subsequent detection of nucleic acids into the cytoplasm constitute a
hallmark of the radiation-induced DNA damage response. However, different radiation …

Hyperpolarized carbon-13 MRI has the advantage of allowing the study of glycolytic flow in
vivo or in vitro dynamically in real-time. The apparent exchange rate constant of a metabolite …

Purpose The existence of cancer stem cells (CSCs) is closely related to tumor recurrence,
metastasis, and resistance to chemoradiotherapy. In addition, given the unique physical and …

Breast carcinomas (BC) are among the most frequent cancers in women. Studies on
radiosensitivity and ionizing radiation response of BC cells are scarce and mainly focused …