Development of polymeric nanoparticles for blood–brain barrier transfer—strategies and challenges
Neurological disorders such as Alzheimer's disease, stroke, and brain cancers are difficult to
treat with current drugs as their delivery efficacy to the brain is severely hampered by the …
treat with current drugs as their delivery efficacy to the brain is severely hampered by the …
Nanoparticle protein corona: from structure and function to therapeutic targeting
Nanoparticle (NP)-based therapeutics have ushered in a new era in translational medicine.
However, despite the clinical success of NP technology, it is not well-understood how NPs …
However, despite the clinical success of NP technology, it is not well-understood how NPs …
Effects of polystyrene nanoparticles on the microbiota and functional diversity of enzymes in soil
Background The increasing production of nanoplastics and the fragmentation of
microplastics into smaller particles suggest a plausible yet unclear hazard in the natural …
microplastics into smaller particles suggest a plausible yet unclear hazard in the natural …
Size-dependent protein–nanoparticle interactions in citrate-stabilized gold nanoparticles: the emergence of the protein corona
Surface modifications of highly monodisperse citrate-stabilized gold nanoparticles (AuNPs)
with sizes ranging from 3.5 to 150 nm after their exposure to cell culture media …
with sizes ranging from 3.5 to 150 nm after their exposure to cell culture media …
Impact of nanoparticles on human and environment: review of toxicity factors, exposures, control strategies, and future prospects
Nanotechnology has revolutionized the world through introduction of a unique class of
materials and consumer products in many arenas. It has led to production of innovative …
materials and consumer products in many arenas. It has led to production of innovative …
Layer-by-layer nanoparticles for systemic codelivery of an anticancer drug and siRNA for potential triple-negative breast cancer treatment
A single nanoparticle platform has been developed through the modular and controlled
layer-by-layer process to codeliver siRNA that knocks down a drug-resistance pathway in …
layer-by-layer process to codeliver siRNA that knocks down a drug-resistance pathway in …
Current understanding of interactions between nanoparticles and the immune system
MA Dobrovolskaia, M Shurin, AA Shvedova - Toxicology and applied …, 2016 - Elsevier
The delivery of drugs, antigens, and imaging agents benefits from using nanotechnology-
based carriers. The successful translation of nanoformulations to the clinic involves thorough …
based carriers. The successful translation of nanoformulations to the clinic involves thorough …
Understanding and exploiting nanoparticles' intimacy with the blood vessel and blood
MI Setyawati, CY Tay, D Docter, RH Stauber… - Chemical Society …, 2015 - pubs.rsc.org
While the blood vessel is seldom the target tissue, almost all nanomedicine will interact with
blood vessels and blood at some point of time along its life cycle in the human body …
blood vessels and blood at some point of time along its life cycle in the human body …
A review on anti-inflammatory activity of green synthesized zinc oxide nanoparticle: Mechanism-based approach
H Agarwal, VK Shanmugam - Bioorganic chemistry, 2020 - Elsevier
Inflammation plays a very important role in the pathogenesis of various diseases like
atherosclerosis, rheumatoid arthritis, asthma, and cancer. Lack of anti-inflammatory drugs …
atherosclerosis, rheumatoid arthritis, asthma, and cancer. Lack of anti-inflammatory drugs …
Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle
Interaction of nanoparticles with proteins is the basis of nanoparticle bio-reactivity. This
interaction gives rise to the formation of a dynamic nanoparticle-protein corona. The protein …
interaction gives rise to the formation of a dynamic nanoparticle-protein corona. The protein …