ApoE is the major lipid and cholesterol carrier in the CNS. There are three major human
polymorphisms, apoE2, apoE3, and apoE4, and the genetic expression of APOE4 is one of …

Neuroinflammation is associated with neurodegenerative diseases, such as Alzheimer's
disease, Parkinson's disease, and amyotrophic lateral sclerosis. Microglia and astrocytes …

Neurodegenerative diseases share the fact that they derive from altered proteins that
undergo an unfolding process followed by formation of β-structures and a pathological …

Alzheimer's disease (AD) is a progressive, mental illness without cure. Several years of
intense research on postmortem AD brains, cell and mouse models of AD have revealed …

Neurodegenerative diseases (NDs) such as Alzheimer disease (AD), Parkinson disease
(PD), and Huntington disease (HD) represent a major socio-economic challenge in view of …

Alzheimer's disease (AD) is the most common cause of progressive dementia in the elderly.
It is characterized by a progressive and irreversible loss of cognitive abilities and formation …

Marine algae are rich in bioactive nutraceuticals (eg, carbohydrates, proteins, minerals, fatty
acids, antioxidants, and pigments). Biotic (eg, plants, microorganisms) and abiotic factors …

Mitochondria are associated with various cellular activities critical to homeostasis,
particularly in the nervous system. The plastic architecture of the mitochondrial network and …

The main features that are commonly attributed to mitochondria consist of the regulation of
cell proliferation, ATP generation, cell death and metabolism. However, recent scientific …

The human microbiota comprises trillions of symbiotic microorganisms and is involved in
regulating gastrointestinal (GI), immune, nervous system and metabolic homeostasis …