Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target …
K Gurdziel, KR Vogt, KD Walton… - Developmental …, 2016 - Wiley Online Library
Background: Digestion is facilitated by coordinated contractions of the intestinal muscularis
externa, a bilayered smooth muscle structure that is composed of inner circular muscles …
externa, a bilayered smooth muscle structure that is composed of inner circular muscles …
NAV3 copy number changes and target genes in basal and squamous cell cancers
P Maliniemi, E Carlsson, A Kaukola… - Experimental …, 2011 - Wiley Online Library
The neuron navigator 3 (NAV3) gene on chromosome 12q21 encodes a microtubule plus
end tracking protein and belongs to the navigator family of cytoskeletal regulators. Loss of …
end tracking protein and belongs to the navigator family of cytoskeletal regulators. Loss of …
Basal cell carcinomas: molecular abnormalities and molecularly targeted therapies
R Dummer, MB Karpova, MJ Barysch - Expert Review of …, 2009 - Taylor & Francis
Basal cell carcinomas (BCCs) are the most common neoplasms in the Caucasian
population. Molecular investigations in basal cell nevus syndrome (Gorlin syndrome) have …
population. Molecular investigations in basal cell nevus syndrome (Gorlin syndrome) have …
[HTML][HTML] GLI1 upregulates C-JUN through a specific 130-kDa isoform
L Amable, E Gavin, K Kudo… - International …, 2014 - spandidos-publications.com
The Hedgehog pathway is molecularly linked to increased resistance to cisplatin and
increased repair of platinum-DNA damage, through C-JUN. GLI1, which has five known …
increased repair of platinum-DNA damage, through C-JUN. GLI1, which has five known …
Multiprotein GLI Transcriptional Complexes as Therapeutic Targets in Cancer
The Hedgehog signaling pathway functions in both embryonic development and adult tissue
homeostasis. Importantly, its aberrant activation is also implicated in the progression of …
homeostasis. Importantly, its aberrant activation is also implicated in the progression of …
SHARPIN regulates cell proliferation of cutaneous basal cell carcinoma via inactivation of the transcriptional factors GLI2 and c‑JUN
Y Yang, YH Liang, Y Zheng… - Molecular …, 2020 - spandidos-publications.com
SHANK‑associated RH domain‑interacting protein (SHARPIN) is a component of the linear
ubiquitin chain assembly complex that can enhance the NF‑κB and JNK signaling pathways …
ubiquitin chain assembly complex that can enhance the NF‑κB and JNK signaling pathways …
From normal development to disease: the biochemistry and regulation of GLI2
AL McCleary-Wheeler - Medical Epigenetics, 2014 - karger.com
GLI2 is an oncogene encoding a unique transcription factor with both repressor and
activator functions. Vitally important in development, it is also thought to be necessary for …
activator functions. Vitally important in development, it is also thought to be necessary for …
[HTML][HTML] Hedgehog signalling pathway: Carcinogenesis and targeted therapy
A Ebrahimi, L Larijani, A Moradi… - Iranian Journal of …, 2013 - ncbi.nlm.nih.gov
Hedgehog signalling pathway has not only a critical role in cell proliferation, differentiation
and tissue polarity at embryonic period but also has a vital role in stem cell proliferation …
and tissue polarity at embryonic period but also has a vital role in stem cell proliferation …
[HTML][HTML] Analysis of new therapeutic strategies for diabetes mellitus based on traditional Chinese medicine “xiaoke” formulae
Q Zhang, R Du, X Hou, Z Lv, C Jia, Y Wang - Journal of Traditional Chinese …, 2018 - Elsevier
Objective To develop new therapeutic strategies for diabetes mellitus (DM) by analyzing the
mechanisms of action of traditional Chinese medicine (TCM)“xiaoke” formulae (TCM …
mechanisms of action of traditional Chinese medicine (TCM)“xiaoke” formulae (TCM …