Redox regulation by NRF2 in aging and disease
NRF2, a transcription factor that has been deemed the master regulator of cellular redox
homeostasis, declines with age. NRF2 transcriptionally upregulates genes that combat …
homeostasis, declines with age. NRF2 transcriptionally upregulates genes that combat …
[HTML][HTML] Abscisic acid and abiotic stress tolerance in crop plants
Abiotic stress is a primary threat to fulfill the demand of agricultural production to feed the
world in coming decades. Plants reduce growth and development process during stress …
world in coming decades. Plants reduce growth and development process during stress …
EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …
A network-biology perspective of microRNA function and dysfunction in cancer
MicroRNAs (miRNAs) participate in most aspects of cellular differentiation and homeostasis,
and consequently have roles in many pathologies, including cancer. These small non …
and consequently have roles in many pathologies, including cancer. These small non …
[HTML][HTML] Antioxidant responses and cellular adjustments to oxidative stress
C Espinosa-Diez, V Miguel, D Mennerich, T Kietzmann… - Redox biology, 2015 - Elsevier
Redox biological reactions are now accepted to bear the Janus faceted feature of promoting
both physiological signaling responses and pathophysiological cues. Endogenous …
both physiological signaling responses and pathophysiological cues. Endogenous …
Epithelialization in wound healing: a comprehensive review
Significance: Keratinocytes, a major cellular component of the epidermis, are responsible for
restoring the epidermis after injury through a process termed epithelialization. This review …
restoring the epidermis after injury through a process termed epithelialization. This review …
Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders
A Kauppinen, T Suuronen, J Ojala, K Kaarniranta… - Cellular signalling, 2013 - Elsevier
Recent studies have indicated that the regulation of innate immunity and energy metabolism
are connected together through an antagonistic crosstalk between NF-κB and SIRT1 …
are connected together through an antagonistic crosstalk between NF-κB and SIRT1 …
MicroRNA regulatory networks in human adipose tissue and obesity
P Arner, A Kulyté - Nature Reviews Endocrinology, 2015 - nature.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and,
therefore, biological processes in different tissues. A major function of miRNAs in adipose …
therefore, biological processes in different tissues. A major function of miRNAs in adipose …
Sox2 induces glioblastoma cell stemness and tumor propagation by repressing TET2 and deregulating 5hmC and 5mC DNA modifications
H Lopez-Bertoni, A Johnson, Y Rui, B Lal… - Signal transduction and …, 2022 - nature.com
DNA methylation is a reversible process catalyzed by the ten–eleven translocation (TET)
family of enzymes (TET1, TET2, TET3) that convert 5-methylcytosine (5mC) to 5 …
family of enzymes (TET1, TET2, TET3) that convert 5-methylcytosine (5mC) to 5 …
[HTML][HTML] Epigenetic alterations in cancer
Genetic and epigenetic modifications in DNA contribute to altered gene expression in aging
and cancer. In human cancers, epigenetic changes such as DNA methylation, histone …
and cancer. In human cancers, epigenetic changes such as DNA methylation, histone …