Adipose tissue is one of the main sources of inflammatory mediators, with interleukin-6 (IL-6)
among them. Although high systemic levels of inflammatory mediators are cachectogenic …

Aliment Pharmacol Ther 2011; 33: 880–894 Summary Background From a classical point of
view, gastric motility acts to clear the stomach between meals, whereas postprandial motility …

Results: In HFD-fed mice, peptibody treatment stimulated muscle growth and improved
insulin resistance. The improved glucose and insulin tolerances were confirmed when we …

Polycystic ovary syndrome (PCOS) is a common endocrine/reproductive/metabolic disorder.
The etiology of PCOS is complex and has been linked to low-grade chronic inflammation …

The prevalence and incidence of asthma have increased among obese children and adults,
particularly among women. Obesity seems to be a predisposing factor for the development …

Diseases originating from altered energy homeostasis including obesity, and type 2
diabetes are rapidly increasing worldwide. Research in the last few decades on animal …

Male infertility is approaching a concerning prevalence worldwide, and inflicts various
impacts on the affected couple. The hormonal assessment is a vital component of male …

Recent studies emphasize the role played by adiponectin in the homeostasis of adipose
tissue and in the pathogenesis of the metabolic syndrome, type 2 diabetes, and …

RATIONALE: Obesity may contribute to the development and clinical expression of asthma.
However, how obesity can influence response to asthma medications is still uncertain …

In the mid-1990s, interest in adipose tissue–until then generally regarded as a mere energy
reserve–was revived by the discovery of leptin. Since then numerous other cytokine-like …