[HTML][HTML] Comparison of gefitinib and erlotinib efficacies as third-line therapy for advanced non-small-cell lung cancer

YY Shao, WY Shau, ZZ Lin, HM Chen, R Kuo… - European Journal of …, 2013 - Elsevier
PURPOSE: The epidermal growth factor receptor inhibitors, gefitinib and erlotinib, are used
as standard salvage therapy for advanced non-small-cell lung cancer (NSCLC). The aim of …

[HTML][HTML] Molecularly targeted therapies for advanced or metastatic non-small-cell lung carcinoma

S Bayraktar, CM Rocha-Lima - World journal of clinical oncology, 2013 - ncbi.nlm.nih.gov
Non-small-cell lung cancer (NSCLC) remains the leading cause of cancer-related death in
both men and women in the United States. Platinum-based doublet chemotherapy has been …

Role of EGFR inhibitors in the treatment of central nervous system metastases from non-small cell lung cancer

GL Ceresoli - Current Cancer Drug Targets, 2012 - ingentaconnect.com
Brain metastases (BM) are a common occurrence in patients with non-small cell lung cancer
(NSCLC). Standard therapy options include whole brain radiotherapy and, in selected …

[HTML][HTML] Inhibition of lung tumor growth in nude mice by siRNACD31 targeting PECAM‑1

JS Ouyang, YP Li, CS Chen, JJ Chen… - Oncology …, 2014 - spandidos-publications.com
Small interfering RNA (siRNA) provides a promising therapeutic approach in the silencing of
disease‑causing genes. In the present study, the use of 2'‑O‑methyl‑modified siRNA‑cluster …

The relationship between short-term surrogate endpoint indicators and mPFS and mOS in clinical trials of malignant tumors: A Case study of approved molecular …

M Rui, Z Wang, Z Fei, Y Wu, Y Wang, L Sun… - Frontiers in …, 2022 - frontiersin.org
Objective: Due to the initiation of the priority review program in China, many antitumor drugs
have been approved for marketing based on phase II clinical trials and short-term surrogate …

Robust Bayesian cumulative probit linear mixed models for longitudinal ordinal data

KJ Lee, RB Chen, K Lee - Computational Statistics, 2024 - Springer
Longitudinal studies have been conducted in various fields, including medicine, economics
and the social sciences. In this paper, we focus on longitudinal ordinal data. Since the …

Risk of selected gastrointestinal toxicities in patients with advanced non-small cell lung cancer receiving erlotinib: a systematic review and meta-analysis

O Abdel-Rahman, M Fouad - Expert Review of Anticancer Therapy, 2015 - Taylor & Francis
We performed a meta-analysis of diarrhea and stomatitis associated with erlotinib use in
patients with advanced non-small cell lung cancer. Eligible studies included randomized …

[PDF][PDF] 厄洛替尼和吉非替尼治疗非小细胞肺癌脑转移的疗效比较

李媛媛, 李莉, 吕恩君 - 中国临床研究, 2018 - zglcyj.cnjournals.com
目的比较厄洛替尼与吉非替尼治疗非小细胞肺癌(NSCLC) 脑转移的临床疗效.
方法回顾性分析2008 年3 月至2014 年3 月收治的73 例NSCLC 患者的临床资料 …

[PDF][PDF] Efikasi Terapi Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor (EGFR-TKIs) pada Kanker Paru

F Wulandari, W Utami, E Rohana, WR Prabhata - 2021 - doc-pak.undip.ac.id
Adanya identifikasi Epidermal Growth Factor Receptor (EGFR) sebagai target molekular
mempengaruhi model terapi kanker paru jenis Non-Small Cell Lung Cancer (NSCLC) …

[HTML][HTML] Osimertinib therapy as first-line treatment before acquiring T790M mutation: from AURA1 trial

K Ito, O Hataji - Journal of Thoracic Disease, 2018 - ncbi.nlm.nih.gov
The AURA1 trial included five patients with EGFR mutation other than exon 19 deletion or
exon 21 L858R point mutation, almost all of which were what we would call uncommon …