Spermatogonial stem cells (SSCs) are the only adult stem cells capable of passing genes
onto the next generation. SSCs also have the potential to provide important knowledge …

Identifying the genes causing male infertility is important to increase our biological
understanding as well as the diagnostic yield and clinical relevance of genetic testing in this …

Centrioles are eukaryotic subcellular structures that produce and regulate massive
cytoskeleton superstructures. They form centrosomes and cilia, regulate new centriole …

This research presents a novel testis-on-a-chip (ToC) platform. Testicular cells are
enzymatically isolated from the seminiferous tubules of sexually immature mice, seeded in a …

Decellularized scaffolds have been found to be excellent platforms for tissue engineering
applications. The attempts are still being made to optimize a decellularization protocol with …

Spermatogenesis is a tightly controlled, multi-step process in which mature spermatozoa are
produced. Disruption of regulatory mechanisms in spermatogenesis can lead to male …

Spermatogenesis is a complex, multistep process during which spermatogonia give rise to
spermatozoa. Transcription Factor Like 5 (TCFL5) is a transcription factor that has been …

Aims This study aimed to explore the effect of epididymosomes on the proliferative efficiency
of spermatogonial stem cells (SSCs) in vitro and the resumption of spermatogenesis in the …

Objective Applications of biological scaffolds for regenerative medicine are increasing. Such
scaffolds improve cell attachment, migration, proliferation and differentiation. In the current …

Background Sperm production is one of the most complex biological processes in the body.
In vitro production of sperm is one of the most important goals of researches in the field of …