Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells
Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) is a dual-function
phosphatase with tumor suppressor function compromised in a wide spectrum of cancers …
phosphatase with tumor suppressor function compromised in a wide spectrum of cancers …
Hyperplastic breast anomalies in the female adolescent breast
EM Wolfswinkel, V Lemaine… - Seminars in Plastic …, 2013 - thieme-connect.com
Macromastia in adolescents is multifactorial and usually idiopathic, associated with obesity
or hormonal imbalances. Less commonly, it can result from virginal or juvenile breast …
or hormonal imbalances. Less commonly, it can result from virginal or juvenile breast …
Mouse models of breast cancer
K Sakamoto, JW Schmidt, KU Wagner - Mouse Models of Cancer: Methods …, 2015 - Springer
Breast cancer is the most common cause of cancer death in women worldwide. This
malignancy is a complex disease, which is defined by an intrinsic heterogeneity on the …
malignancy is a complex disease, which is defined by an intrinsic heterogeneity on the …
[HTML][HTML] PTEN: new insights into its regulation and function in skin cancer
Skin cancer is the most common cancer in the United States. UV radiation in sunlight is the
major environmental factor causing skin cancer development. PTEN (phosphatase and …
major environmental factor causing skin cancer development. PTEN (phosphatase and …
PTEN deficiency in a luminal ErbB-2 mouse model results in dramatic acceleration of mammary tumorigenesis and metastasis
Overexpression and/or amplification of the ErbB-2 oncogene as well as inactivation of the
PTEN tumor suppressor are two important genetic events in human breast carcinogenesis …
PTEN tumor suppressor are two important genetic events in human breast carcinogenesis …
Breast reduction in adolescents: indication, timing, and a review of the literature
AS Xue, EM Wolfswinkel, WM Weathers… - Journal of pediatric and …, 2013 - Elsevier
Background Adolescent breast hypertrophy can have long-term negative medical and
psychological impacts. In select patients, breast reduction surgery is the best treatment …
psychological impacts. In select patients, breast reduction surgery is the best treatment …
PTEN and p53 cross-regulation induced by soy isoflavone genistein promotes mammary epithelial cell cycle arrest and lobuloalveolar differentiation
OM Rahal, RCM Simmen - Carcinogenesis, 2010 - academic.oup.com
The tumor suppressors phosphatase and tensin homologue deleted on chromosome ten
(PTEN) and p53 are closely related to the pathogenesis of breast cancer, yet pathway …
(PTEN) and p53 are closely related to the pathogenesis of breast cancer, yet pathway …
Microarray analysis of the involution switch
RWE Clarkson, CJ Watson - Journal of mammary gland biology and …, 2003 - Springer
Mammary epithelial cells (MEC) undergo a series of developmental decisions during a
pregnancy cycle. The switches from proliferation to differentiation to secretion and then to …
pregnancy cycle. The switches from proliferation to differentiation to secretion and then to …
An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias
C Mirantes, N Eritja, MA Dosil… - Disease models & …, 2013 - journals.biologists.com
SUMMARY PTEN is one of the most frequently mutated tumor suppressor genes in human
cancers. The role of PTEN in carcinogenesis has been validated by knockout mouse …
cancers. The role of PTEN in carcinogenesis has been validated by knockout mouse …
Virginal mammary hypertrophy: a meta-analysis and treatment algorithm
IC Hoppe, PP Patel, CJ Singer-Granick… - Plastic and …, 2011 - journals.lww.com
Background: Virginal mammary hypertrophy, a rapid enlargement of one or both breasts that
usually presents in the adolescent years, is a rare condition that has been reported …
usually presents in the adolescent years, is a rare condition that has been reported …