Metabolic profiles of regulatory T cells and their adaptations to the tumor microenvironment: implications for antitumor immunity

Y Yan, L Huang, Y Liu, M Yi, Q Chu, D Jiao… - Journal of hematology & …, 2022 - Springer
Characterized by the expression of the critical transcription factor forkhead box protein P3,
regulatory T (Treg) cells are an essential part of the immune system, with a dual effect on the …

Metabolic pathways involved in regulatory T cell functionality

RWM Kempkes, I Joosten, HJPM Koenen… - Frontiers in …, 2019 - frontiersin.org
Regulatory T cells (Treg) are well-known for their immune regulatory potential and are
essential for maintaining immune homeostasis. The rationale of Treg-based immunotherapy …

Effects of flavonoids and its derivatives on immune cell responses

G Martínez, MR Mijares… - Recent Patents on …, 2019 - ingentaconnect.com
Background: Various pieces of evidence have shown that people who consume foods rich in
polyphenolic and flavonoids compounds have a lower incidence of inflammatory …

Immunological mechanisms in allergic diseases and allergen tolerance: the role of Treg cells

D Calzada, S Baos… - Journal of …, 2018 - Wiley Online Library
The immune system regulates itself to establish an appropriate immune response to
potentially harmful pathogens while tolerating harmless environmental antigens and self …

Orally desensitized mast cells form a regulatory network with Treg cells for the control of food allergy

Y Takasato, Y Kurashima, M Kiuchi, K Hirahara… - Mucosal …, 2021 - nature.com
Oral immunotherapy (OIT) is an effective approach to controlling food allergy. Although the
detailed molecular and cellular mechanisms of OIT are unknown currently, they must be …

Long non-coding RNA DQ786243 modulates the induction and function of CD4+ Treg cells through Foxp3-miR-146a-NF-κB axis: Implications for alleviating oral …

J Wang, X Zhai, J Guo, Y Li, Y Yang, L Wang… - International …, 2019 - Elsevier
The present study was aimed to investigate the effects of the long non-coding RNA
DQ786243 in the regulation of Treg cells in oral lichen planus (OLP), as well as to evaluate …

Forkhead box p3 controls progression of oral lichen planus by regulating microRNA‐146a

J Wang, L Yang, L Wang, Y Yang… - Journal of Cellular …, 2018 - Wiley Online Library
Oral lichen planus (OLP) is a severe T cell–mediated disorder of the mucosa, which causes
chronic inflammation. Forkhead box P3 (Foxp3) regulates the immune response and plays …

Characteristic features of in vitro differentiation of human naïve CD4+ T cells to induced regulatory T cells (iTreg) and T helper (Th) 17 cells: Sharing of lineage-specific …

J Soongsathitanon, T Homjan, S Pongcharoen - Heliyon, 2024 - cell.com
In vitro induced regulatory T cells (iTreg) and IL-17 producing T cells (Th17-like cells) can be
generated in culture from native CD4+ T cells in peripheral blood by different sets of …

[HTML][HTML] 早产儿异基因细胞移植免疫耐受的研究进展

屈艺 - Chinese Journal of Contemporary Pediatrics, 2018 - ncbi.nlm.nih.gov
早产儿是一类特殊的群体, 与早产相关的严重神经、 呼吸、 消化系统疾病的致残/致死率居高
不下。 异基因细胞移植可能是上述疾病治疗和预防的有效手段。 目前, 异基因细胞移植治疗缺 …

Células T regulatorias en ratones con diferente susceptibilidad al desarrollo de enfermedades autoinmunes

GJ Godoy - 2019 - ri.conicet.gov.ar
Las células T regulatorias (Treg), una subpoblación de linfocitos T (LT) CD4+, son
fundamentales para el mantenimiento de la tolerancia inmune hacia antígenos propios y …