Metabolic reprogramming and epigenetic modifications are hallmarks of cancer cells. In
cancer cells, metabolic pathway activity varies during tumorigenesis and cancer …

Drug resistance is mainly responsible for cancer recurrence and poor prognosis. Epigenetic
regulation is a heritable change in gene expressions independent of nucleotide sequence …

Background Recently, the hallmarks of aging were updated to include dysbiosis, disabled
macroautophagy, and chronic inflammation. In particular, the low-grade chronic …

MicroRNAs (miRNAs) are a group of small non-coding RNAs that post-transcriptionally
control expression of genes by targeting mRNAs. miRNA alterations partake in the …

Mitochondria are not only the main energy supplier but are also the cell metabolic center
regulating multiple key metaborates that play pivotal roles in epigenetics regulation. These …

Histones are DNA‐binding basic proteins found in chromosomes. After the histone
translation, its amino tail undergoes various modifications, such as methylation, acetylation …

Lung cancer (LC) is the main cause of cancer-related mortality. Most LC patients are
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …

The trace element selenium (Se) is an essential part of the human diet; moreover, increased
health risks have been observed with Se deficiency. A sufficiently high Se status is a …

Cancer is a global public health concern. Alterations in epigenetic processes are among the
earliest genomic aberrations occurring during cancer development and are closely related …

MEG3, a significant long non-coding RNA (lncRNA), substantially functions in diverse
biological processes, particularly breast cancer (BC) development. Within the imprinting …