Growth hormone-releasing hormone receptor signaling in experimental ocular inflammation and neuroprotection

LP Cen, TK Ng, WK Chu, CP Pang - Neural Regeneration …, 2022 - journals.lww.com
Both inflammation and anti-inflammation are involved in the protection of retinal cells.
Antagonists of the hypothalamic growth hormone-releasing hormone receptor (GHRHR) …

Agonist of growth hormone-releasing hormone improves the disease features of spinal muscular atrophy mice

M Boido, I Gesmundo, A Caretto… - Proceedings of the …, 2023 - National Acad Sciences
Spinal muscular atrophy (SMA) is a severe autosomal recessive neuromuscular disease
affecting children and young adults, caused by mutations of the survival motor neuron 1 …

[HTML][HTML] Antagonist of growth hormone-releasing hormone MIA-690 attenuates the progression and inhibits growth of colorectal cancer in mice

L Recinella, A Chiavaroli, S Veschi, V Di Valerio… - Biomedicine & …, 2022 - Elsevier
Colorectal cancer (CRC) is an aggressive tumor in which new treatment options deliver
negative results on cure rates and long-term survival. The anticancer effects of growth …

Effects of GHRH Deficiency and GHRH Antagonism on Emotional Disorders in Mice

L Recinella, ML Libero, S Veschi, A Piro, GD Marconi… - Cells, 2023 - mdpi.com
Growth hormone (GH)-releasing hormone (GHRH) has been suggested to play a crucial role
in brain function. We aimed to further investigate the effects of a novel GHRH antagonist of …