Silk nanoparticles: From inert supports to bioactive natural carriers for drug delivery

B Crivelli, S Perteghella, E Bari, M Sorrenti, G Tripodo… - Soft Matter, 2018 - pubs.rsc.org
Silk proteins have been studied and employed for the production of drug delivery (nano)
systems. They show excellent biocompatibility, controllable biodegradability and non …

Emerging trends in silk fibroin based nanofibers for impaired wound healing

G Sabarees, GP Tamilarasi, V Velmurugan… - Journal of Drug Delivery …, 2023 - Elsevier
Drug delivery systems based on the silk fibroin (SF) protein have attracted a lot of attention
because of the protein's less immunogenicity, ease of sterilizing, processability without …

Silk materials at the convergence of science, sustainability, healthcare, and technology

G Guidetti, L d'Amone, T Kim, G Matzeu… - Applied Physics …, 2022 - pubs.aip.org
Over the past few decades, Bombyx mori silk fibroin has become a ubiquitous material for
applications ranging from biomedical devices to optics, electronics, and sensing, while also …

Silk fibroin nanoparticles for celecoxib and curcumin delivery: ROS-scavenging and anti-inflammatory activities in an in vitro model of osteoarthritis

B Crivelli, E Bari, S Perteghella, L Catenacci… - European Journal of …, 2019 - Elsevier
This paper aims at demonstrating silk fibroin nanoparticles (SFNs) promote anti-
inflammatory properties of celecoxib (CXB) or curcumin (CUR), and could be exploited for …

Polydopamine-assisted silver nanoparticle self-assembly on sericin/agar film for potential wound dressing application

L Liu, R Cai, Y Wang, G Tao, L Ai, P Wang… - International journal of …, 2018 - mdpi.com
Silver nanoparticles (AgNPs) are extensively applied for their broad-spectrum and excellent
antibacterial ability in recent years. Polydopamine (PDA) has great advantages for …

Stem cell-extracellular vesicles as drug delivery systems: New frontiers for silk/curcumin nanoparticles

S Perteghella, B Crivelli, L Catenacci, M Sorrenti… - International journal of …, 2017 - Elsevier
The aim of this work was to develop a novel carrier-in-carrier system based on stem cell-
extracellular vesicles loaded of silk/curcumin nanoparticles by endogenous technique. Silk …

Facilely printed silk fibroin hydrogel microparticles as injectable long-lasting fillers

C Xie, X Yang, F Zheng, J Shi, C Huo, Z Wang… - Biomaterials …, 2024 - pubs.rsc.org
There is a high demand from aging people for facial fillers with desirable biocompatibility
and lasting filling effects to overcome facial depression. Novel injectable regenerated silk …

GMP-compliant sponge-like dressing containing MSC lyo-secretome: Proteomic network of healing in a murine wound model

E Bari, D Di Silvestre, L Mastracci, F Grillo… - European Journal of …, 2020 - Elsevier
Chronic wounds account for 3% of total healthcare expenditure of developed countries; thus,
innovative therapies, including Mesenchymal Stem Cells (MSCs) end their exosomes are …

[HTML][HTML] Growth factors delivery system for skin regeneration: An advanced wound dressing

M Nardini, S Perteghella, L Mastracci, F Grillo… - Pharmaceutics, 2020 - mdpi.com
Standard treatments of chronic skin ulcers based on the direct application of dressings still
present several limits with regard to a complete tissue regeneration. Innovative strategies in …

Association of silk sericin and platelet lysate: Premises for the formulation of wound healing active medications

E Bari, S Perteghella, S Faragò, ML Torre - International journal of …, 2018 - Elsevier
Silk sericin (SS), a globular and water-soluble protein, showed to in vitro sustain the
proliferation of different mammalian cell lines, and to in vitro protect them from the oxidative …