Primary glaucomas in adults: Epidemiology and public health‐A review

TF Reis, JS Paula, JM Furtado - Clinical & experimental …, 2022 - Wiley Online Library
Glaucoma is a mixed group of optic neuropathies that lead to irreversible visual field loss
and blindness if left untreated. It is estimated that 3.5% of the global population aged 40 to …

[HTML][HTML] Associations with intraocular pressure in a large cohort: results from the UK Biobank

MPY Chan, CM Grossi, AP Khawaja, JLY Yip, KT Khaw… - Ophthalmology, 2016 - Elsevier
Purpose To describe the associations of physical and demographic factors with Goldmann-
correlated intraocular pressure (IOPg) and corneal-compensated intraocular pressure …

Detecting retinal cell stress and apoptosis with DARC: Progression from lab to clinic

MF Cordeiro, D Hill, R Patel, P Corazza… - Progress in Retinal and …, 2022 - Elsevier
Abstract DARC (Detection of Apoptosing Retinal Cells) is a retinal imaging technology that
has been developed within the last 2 decades from basic laboratory science to Phase 2 …

Primary open angle glaucoma prevalence in Europe: a systematic review and meta-analysis

GG Afflitto, F Aiello, M Cesareo, C Nucci - Journal of Glaucoma, 2022 - journals.lww.com
Purpose: This study aimed to evaluate the prevalence of POAG in Europe. Methods: Two
authors independently conducted a systematic literature search on PubMed/MedLine, Web …

Efficacy and safety of different regimens for primary open‐angle glaucoma or ocular hypertension: a systematic review and network meta‐analysis

F Li, W Huang, X Zhang - Acta ophthalmologica, 2018 - Wiley Online Library
Purpose To assess the efficacy and safety of different regimens, including monotherapy and
double therapy, for primary open‐angle glaucoma (POAG) or ocular hypertension. Methods …

[HTML][HTML] Changes of visual pathway and brain connectivity in glaucoma: a systematic review

R Nuzzi, L Dallorto, T Rolle - Frontiers in Neuroscience, 2018 - frontiersin.org
Background: Glaucoma is a leading cause of irreversible blindness worldwide. The
increasing interest in the involvement of the cortical visual pathway in glaucomatous patients …

[HTML][HTML] Myocilin-associated glaucoma: a historical perspective and recent research progress

R Sharma, A Grover - Molecular Vision, 2021 - ncbi.nlm.nih.gov
Glaucoma a debilitating disease, is globally the second most common kind of permanent
blindness. Primary open-angle glaucoma (POAG) is its most prevalent form and is often …

Glaucoma and blood pressure

M Leeman, P Kestelyn - Hypertension, 2019 - Am Heart Assoc
The pathogenesis of glaucoma is incompletely understood, but the death of axons grouped
together at the optic disc implies that this anatomic area is primarily involved. The typical …

[HTML][HTML] Autophagy stimulation reduces ocular hypertension in a murine glaucoma model via autophagic degradation of mutant myocilin

RB Kasetti, P Maddineni, C Kiehlbauch, S Patil… - JCI insight, 2021 - ncbi.nlm.nih.gov
Elevation of intraocular pressure (IOP) due to trabecular meshwork (TM) damage is
associated with primary open-angle glaucoma (POAG). Myocilin mutations resulting in …

Effect of vitamin-E integration on delivery of prostaglandin analogs from therapeutic lenses

P Sekar, A Chauhan - Journal of colloid and interface science, 2019 - Elsevier
Hypothesis Glaucoma is effectively treated by prostaglandin analogs. Low corneal
bioavailability (< 5%) of daily-instilled prostaglandin drops complemented by frequent …