Fusobacterium nucleatum — symbiont, opportunist and oncobacterium

CA Brennan, WS Garrett - Nature Reviews Microbiology, 2019 - nature.com
Fusobacterium nucleatum has long been found to cause opportunistic infections and has
recently been implicated in colorectal cancer; however, it is a common member of the oral …

Prognostic and predictive molecular biomarkers for colorectal cancer: updates and challenges

E Koncina, S Haan, S Rauh, E Letellier - Cancers, 2020 - mdpi.com
Colorectal cancer (CRC) is a leading cause of death among cancer patients. This
heterogeneous disease is characterized by alterations in multiple molecular pathways …

scPred: accurate supervised method for cell-type classification from single-cell RNA-seq data

J Alquicira-Hernandez, A Sathe, HP Ji, Q Nguyen… - Genome biology, 2019 - Springer
Single-cell RNA sequencing has enabled the characterization of highly specific cell types in
many tissues, as well as both primary and stem cell-derived cell lines. An important facet of …

Angiogenesis and anti-angiogenic treatment in prostate cancer: mechanisms of action and molecular targets

E Ioannidou, M Moschetta, S Shah, JS Parker… - International journal of …, 2021 - mdpi.com
Prostate cancer (PC) is the most common cancer in men and the second leading cause of
cancer-related death worldwide. Many therapeutic advances over the last two decades have …

Molecular pathogenesis of colorectal cancer with an emphasis on recent advances in biomarkers, as well as nanotechnology-based diagnostic and therapeutic …

FA Al-Joufi, A Setia, MM Salem-Bekhit, RK Sahu… - Nanomaterials, 2022 - mdpi.com
Colorectal cancer (CRC) is a serious disease that affects millions of people throughout the
world, despite considerable advances in therapy. The formation of colorectal adenomas and …

Unraveling the wide spectrum of melanoma biomarkers

A Revythis, S Shah, M Kutka, M Moschetta, MA Ozturk… - Diagnostics, 2021 - mdpi.com
The use of biomarkers in medicine has become essential in clinical practice in order to help
with diagnosis, prognostication and prediction of treatment response. Since Alexander …

The clinical relevance of gene expression based prognostic signatures in colorectal cancer

P Ahluwalia, R Kolhe, GK Gahlay - … et Biophysica Acta (BBA)-Reviews on …, 2021 - Elsevier
Colorectal cancer (CRC) is one of the most prevalent cancers, with more than one million
new cases every year. In the last few decades, several advancements in therapeutic and …

Microsatellite instability testing in colorectal patients with Lynch syndrome: lessons learned from a case report and how to avoid such pitfalls

S Adeleke, A Haslam, A Choy, S Diaz-Cano… - Personalized …, 2022 - Taylor & Francis
We present the case of a patient with Lynch syndrome and metastatic colorectal carcinoma
(mCRC). The initial immunohistochemistry (IHC) test for deficient mismatch repair gave a …

The developing story of predictive biomarkers in colorectal cancer

S Boussios, MA Ozturk, M Moschetta… - Journal of personalized …, 2019 - mdpi.com
Colorectal cancer (CRC) is the third most common malignancy worldwide. Surgery remains
the most important treatment for non-metastatic CRC, and the administration of adjuvant …

KRAS, NRAS, BRAF, HER2 and microsatellite instability in metastatic colorectal cancer–practical implications for the clinician

VA Afrăsânie, MV Marinca, T Alexa-Stratulat… - Radiology and …, 2019 - sciendo.com
Methods A search algorithm (Figure 1) based on a combination of the terms ''metastatic
colorectal cancer''AND “therapy” OR “treatment” AND “RAS” OR “KRAS” OR “NRAS” AND …