The transcription factor family activator protein 2 (TFAP2) is vital for regulating both
embryonic and oncogenic development. The TFAP2 family consists of five DNA-binding …

Nicorandil ameliorated doxorubicin-induced nephrotoxicity; this study aimed to show and
explain the mechanism of this protection. A precise method was elucidated to study the …

Monoaminergic neurotransmitter systems play a central role in neuronal function and
behaviour. Dysregulation of these systems gives rise to neuropsychiatric and …

Background Among all causes of death, cancer is the most prevalent and is only outpaced
by cardiovascular diseases. Molecular theory of carcinogenesis states that apoptosis and …

Simple Summary A prognostic factor of bladder cancer which can benefit from research on
molecular markers is the histologic grade. WWOX, AP-2α and AP-2γ are known to have a …

Background: Neuroblastoma is the most common extracranial solid tumor in childhood.
Amplification of MYCN in neuroblastoma is a predictor of poor prognosis. Materials and …

TFAP2E is a member of the activator protein-2 transcription factor family and acts as a tumor
suppressor in several types of cancer. Downregulation of TFAP2E expression is significantly …

AP-2 transcription factors play important roles in the regulation of gene expression during
development. Four of the five members of the AP-2 family (AP-2α, AP-2β, AP-2γ and AP-2δ) …

Doxorubic in nephrotoxicity is always a major cause of death for cancer patients. objectives:
our study aimed at proving the potential curative mechanisms of sodium thiosulphate, on …

The AP-2 family of transcription factors consist of DNA-binding proteins: AP-2α to AP-2ε.
Members and homologs of this family are also known in frogs, fish and invertebrates. These …