The Cryptococcus neoformans capsule: a sword and a shield

TR O'Meara, JA Alspaugh - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

Mitogen-activated protein kinase pathways and fungal pathogenesis

X Zhao, R Mehrabi, JR Xu - Eukaryotic cell, 2007 - Am Soc Microbiol
In eukaryotic cells, a family of serine/threonine protein kinases known as mitogen-activated
protein (MAP) kinases (MAPKs) is involved in the transduction of a variety of extracellular …

[HTML][HTML] Cryptococcus neoformans adapts to the host environment through TOR-mediated remodeling of phospholipid asymmetry

LC Ristow, AJ Jezewski, BJ Chadwick… - Nature …, 2023 - nature.com
Cryptococcus spp. are environmental fungi that first must adapt to the host environment
before they can cause life-threatening meningitis in immunocompromised patients. Host …

Identification of fungal cell wall mutants using susceptibility assays based on Calcofluor white and Congo red

AFJ Ram, FM Klis - Nature protocols, 2006 - nature.com
The fungal cell wall is an essential organelle and represents a considerable metabolic
investment. Its macromolecular composition, molecular organization and thickness can vary …

Our paths might cross: the role of the fungal cell wall integrity pathway in stress response and cross talk with other stress response pathways

BB Fuchs, E Mylonakis - Eukaryotic cell, 2009 - Am Soc Microbiol
Fungi occupy diverse environments and are subjected to many extreme conditions. Among
the stressful conditions faced by fungi are pH changes, osmotic changes, thermal changes …

Virulence-associated enzymes of Cryptococcus neoformans

F Almeida, JM Wolf, A Casadevall - Eukaryotic cell, 2015 - Am Soc Microbiol
Enzymes play key roles in fungal pathogenesis. Manipulation of enzyme expression or
activity can significantly alter the infection process, and enzyme expression profiles can be a …

[HTML][HTML] Cryptococcal pathogenic mechanisms: a dangerous trip from the environment to the brain

SK Esher, O Zaragoza, JA Alspaugh - Memorias do Instituto Oswaldo …, 2018 - SciELO Brasil
Cryptococcus neoformans is an opportunistic pathogenic yeast that causes serious
infections, most commonly of the central nervous system (CNS). C. neoformans is mainly …

The bacterial lipopeptide iturins induce Verticillium dahliae cell death by affecting fungal signalling pathways and mediate plant defence responses involved in …

Q Han, F Wu, X Wang, H Qi, L Shi… - Environmental …, 2015 - Wiley Online Library
V erticillium wilt in cotton caused by V erticillium dahliae is one of the most serious plant
diseases worldwide. Because no known fungicides or cotton cultivars provide sufficient …

A Chitin Synthase and Its Regulator Protein Are Critical for Chitosan Production and Growth of the Fungal Pathogen Cryptococcus neoformans

IR Banks, CA Specht, MJ Donlin, KJ Gerik… - Eukaryotic …, 2005 - Am Soc Microbiol
Chitin is an essential component of the cell wall of many fungi. Chitin also can be
enzymatically deacetylated to chitosan, a more flexible and soluble polymer. Cryptococcus …

[HTML][HTML] An Extensive Circuitry for Cell Wall Regulation in Candida albicans

JR Blankenship, S Fanning, JJ Hamaker… - PLoS …, 2010 - journals.plos.org
Protein kinases play key roles in signaling and response to changes in the external
environment. The ability of Candida albicans to quickly sense and respond to changes in its …