Reactive oxygen species (ROS) are produced in the course of normal metabolism and they
serve important physiological functions. However, because of their high reactivity …

Nitric oxide and other reactive nitrogen species appear to play several crucial roles in the
brain. These include physiological processes such as neuromodulation, neurotransmission …

Inducible nitric oxide synthase (iNOS) is induced by inflammatory cytokines in skeletal
muscle and fat. It has been proposed that chronic iNOS induction may cause muscle insulin …

Many proteins exert their biological roles as components of complexes, and the functions of
proteins are often determined by their specific interactions with other proteins. Because of …

Abstract: Emerging data indicate that growth factors such as insulin-like growth factor-1 (IGF-
1) prevent neuronal death due to nitric oxide (NO) toxicity. On the other hand, growth factors …

Nitric oxide and other reactive nitrogen species appear to play crucial roles in the brain such
as neuromodulation, neurotransmission and synaptic plasticity, but are also involved in …

Potent and selective inhibitors of inducible nitric oxide synthase (iNOS)(EC 1.14. 13.39)
were identified in an encoded combinatorial chemical library that blocked human iNOS …

The free-radical gas nitric oxide (NO) plays an important role in a diverse range of
physiological processes. It is synthesized from the precursor l-arginine by the enzyme NO …

The aim of the present study was to investigate the role of GABAergic and nitriergic
modulation in the antianxiety effect of thymoquinone, a major constituent of Nigella sativa, in …

Both underproduction and overproduction of nitric oxide (NO) could lead to various eye
diseases. It is known that endothelial NO synthase (eNOS) and neuronal NOS (nNOS) are …