Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety

MA Hannan, MA Rahman, AAM Sohag, MJ Uddin… - Nutrients, 2021 - mdpi.com
Mounting evidence support the potential benefits of functional foods or nutraceuticals for
human health and diseases. Black cumin (Nigella sativa L.), a highly valued nutraceutical …

Natural products can be used in therapeutic management of COVID-19: Probable mechanistic insights

S Ali, M Alam, F Khatoon, U Fatima, AM Elasbali… - Biomedicine & …, 2022 - Elsevier
The unexpected emergence of the new Coronavirus disease (COVID-19) has affected more
than three hundred million individuals and resulted in more than five million deaths …

[HTML][HTML] Nigella sativa for the treatment of COVID-19: An open-label randomized controlled clinical trial

AE Koshak, EA Koshak, AF Mobeireek… - … Therapies in Medicine, 2021 - Elsevier
Abstract Background Effective treatment for Coronavirus Disease-2019 (COVID-19) is under
intensive research. Nigella sativa oil (NSO) is a herbal medicine with antiviral and …

Nigella sativa L. Phytochemistry and Pharmacological Activities: A Review (2019–2021)

M Dalli, O Bekkouch, S Azizi, A Azghar, N Gseyra… - Biomolecules, 2021 - mdpi.com
Medicinal and aromatic plants are mainly characterized by the presence of different
bioactive compounds which exhibit various therapeutic activities. In order to investigate the …

Honey and Nigella sativa against COVID‐19 in Pakistan (HNS‐COVID‐PK): A multicenter placebo‐controlled randomized clinical trial

S Ashraf, S Ashraf, M Ashraf, MA Imran… - Phytotherapy …, 2023 - Wiley Online Library
Until now, no specific and effective treatment exists for coronavirus disease 2019 (COVID‐
19). Since honey and Nigella sativa (HNS) have established antiviral, antibacterial …

Thymoquinone: A promising natural compound with potential benefits for COVID-19 prevention and cure

OA Badary, MS Hamza, R Tikamdas - Drug design, development …, 2021 - Taylor & Francis
COVID-19 has caused a major global health crisis, as excessive inflammation, oxidation,
and exaggerated immune response in some sufferers can lead to a condition known as …

A review on measures to rejuvenate immune system: Natural mode of protection against coronavirus infection

MA Islam, MA Haque, MA Rahman, F Hossen… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2, a novel Corona virus strain, was first detected in Wuhan, China, in December
2019. As of December 16, 2021, almost 4,822,472 people had died and over 236,132,082 …

The role of thymoquinone, a major constituent of Nigella sativa, in the treatment of inflammatory and infectious diseases

K Fatima Shad, W Soubra… - Clinical and Experimental …, 2021 - Wiley Online Library
Nigella sativa (N. sativa) is an annual flowering plant that has been used as a traditional
remedy for many centuries. The seed possesses a large variety of compounds with …

[HTML][HTML] Anticancer properties and mechanism insights of α-hederin

O Belmehdi, D Taha, J Abrini, LC Ming, A Khalid… - Biomedicine & …, 2023 - Elsevier
Abstract α-Hederin is a natural bioactive molecule very abundant in aromatic and medicinal
plants (AMP). It was identified, characterized, and isolated using different extraction and …

Metabolomics driven analysis of Nigella sativa seeds identifies the impact of roasting on the chemical composition and immunomodulatory activity

MA Salem, RA El-Shiekh, NM Aborehab… - Food Chemistry, 2023 - Elsevier
Nigella sativa L. seeds (NS) are known as one of the most traditional immunomodulatory
and nutritive food additives. NS can, furthermore, be roasted to give curries, breads, and …