In recent years, the existing relationship between excess overweight and central precocious
puberty (CPP) has been reported, especially in girls. Different nutritional choices have been …

Objectives The aim of this study was to evaluate the potential association between early
onset puberty and the risk of different forms of obesity in children. Methods The databases …

Background Over the last few decades, there has been growing evidence of earlier onset
and progression of puberty worldwide. This population-based longitudinal cohort study …

Obesity is a complex chronic condition associated with multiple health risks, including
visceral obesity, which is particularly detrimental. To gain insight into the mechanisms …

To study the levels of serum insulin-like growth factor 1 (IGF-1), fibroblast growth factor 23
(FGF23), and Klotho, and to study their relationship with girls with rapidly progressive central …

To assess the association between serum copper/zinc ratio (CZR) and overweight/obesity in
children. Sociodemographic and clinical data of children aged 8–18 years old were …

Background To investigate serum irisin levels in girls at different developmental status and
explore the significance of irisin for the diagnosis of central precocious puberty (CPP) in …

Childhood obesity with its growing prevalence worldwide presents one of the most important
health challenges nowadays. Multiple mechanisms are involved in the development of this …

Background: A correlation between plasma lipids and timing of pubertal development has
been hypothesized, though lipid influence remains unclear in central precocious puberty …

Introduction: BMI or BMI-standardized deviation score (SDS) in children and adolescents is
still the standard for weight classification.[BMJ. 2019; 366: 4293] developed a formula to …