Exosomal biomarkers for cancer diagnosis and patient monitoring

A Makler, W Asghar - Expert review of molecular diagnostics, 2020 - Taylor & Francis
Introduction: In recent years, extensive research has been conducted on using exosomes as
biomarkers for cancer detection. Exosomes are 40–150 nm-sized extracellular vesicles …

IVF-on-a-chip: recent advances in microfluidics technology for in vitro fertilization

L Weng - SLAS TECHNOLOGY: Translating Life Sciences …, 2019 - journals.sagepub.com
In vitro fertilization (IVF) has been one of the most exciting modern medical technologies. It
has transformed the landscape of human infertility treatment. However, current IVF …

Sperm quality metrics were improved by a biomimetic microfluidic selection platform compared to swim-up methods

SA Vasilescu, L Ding, FY Parast, R Nosrati… - Microsystems & …, 2023 - nature.com
Sperm selection is an essential component of all assisted reproductive treatments (ARTs)
and is by far the most neglected step in the ART workflow in regard to technological …

Surface acoustic wave-driven pumpless flow for sperm rheotaxis analysis

J Gai, C Devendran, A Neild, R Nosrati - Lab on a Chip, 2022 - pubs.rsc.org
Sperm rheotaxis, the phenomenon where sperm cells swim against the direction of fluid
flow, is one of the major guiding mechanisms for long-distance sperm migration within the …

Development of a novel cervix-inspired tortuous microfluidic system for efficient, high-quality sperm selection

E Dadkhah, MA Hajari, S Abdorahimzadeh… - Lab on a Chip, 2023 - pubs.rsc.org
Microfluidic systems have been extensively studied in recent years as potential alternatives
for problematic conventional methods of sperm selection. However, despite the widespread …

Development of a flow-free magnetic actuation platform for an automated microfluidic ELISA

C Coarsey, B Coleman, MA Kabir, M Sher, W Asghar - RSC advances, 2019 - pubs.rsc.org
There is a need to create an easily deployable and point-of-care (POC) diagnostic platform
for disease outbreaks and for monitoring and maintenance of chronic illnesses. Such …

Lab-on-a-chip zika detection with reverse transcription Loop-mediated isothermal amplification–based assay for point-of-care settings

S Sharma, MA Kabir, W Asghar - Archives of pathology & …, 2020 - meridian.allenpress.com
Context.—Zika virus (ZIKV) infection, primarily transmitted by mosquitoes, causes various
neurologic disorders. To differentiate ZIKV from other arboviruses, such as dengue …

Smartphone-based sickle cell disease detection and monitoring for point-of-care settings

S Ilyas, M Sher, E Du, W Asghar - Biosensors and Bioelectronics, 2020 - Elsevier
Sickle cell disease (SCD) is a worldwide hematological disorder causing painful episodes,
anemia, organ damage, stroke, and even deaths. It is more common in sub-Saharan Africa …

Pump-Free Microfluidic Device for the Electrochemical Detection of α1-Acid Glycoprotein

T Sierra, I Jang, E Noviana, AG Crevillen… - ACS …, 2021 - ACS Publications
α1-Acid glycoprotein (AGP) is a glycoprotein present in serum, which is associated with the
modulation of the immune system in response to stress or injuries, and a biomarker for …

Selection of healthy sperm based on positive rheotaxis using a microfluidic device

S Sharma, MA Kabir, W Asghar - Analyst, 2022 - pubs.rsc.org
For conception, sperm cells travel towards the oocyte. This journey is accomplished by only
a few sperm cells, following various guidance mechanisms. Of these mechanisms, rheotaxis …