[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …
[HTML][HTML] G protein-coupled receptors: structure-and function-based drug discovery
D Yang, Q Zhou, V Labroska, S Qin… - Signal transduction and …, 2021 - nature.com
As one of the most successful therapeutic target families, G protein-coupled receptors
(GPCRs) have experienced a transformation from random ligand screening to knowledge …
(GPCRs) have experienced a transformation from random ligand screening to knowledge …
Structural impact on SARS-CoV-2 spike protein by D614G substitution
Substitution for aspartic acid (D) by glycine (G) at position 614 in the spike (S) protein of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears to facilitate rapid …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears to facilitate rapid …
[HTML][HTML] Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course
J Muri, V Cecchinato, A Cavalli, AA Shanbhag… - Nature …, 2023 - nature.com
Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse
symptoms, which can persist for months. While antiviral antibodies are protective, those …
symptoms, which can persist for months. While antiviral antibodies are protective, those …
Molecular mechanism of HIV-1 entry
B Chen - Trends in microbiology, 2019 - cell.com
HIV-1 envelope glycoprotein [Env; trimeric (gp160) 3 cleaved to (gp120/gp41) 3] attaches
the virion to a susceptible cell and induces fusion of viral and cell membranes to initiate …
the virion to a susceptible cell and induces fusion of viral and cell membranes to initiate …
[HTML][HTML] Ultrasensitive high-resolution profiling of early seroconversion in patients with COVID-19
Sensitive assays are essential for the accurate identification of individuals infected with
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we report a …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we report a …
[PDF][PDF] Virus-receptor interactions of glycosylated SARS-CoV-2 spike and human ACE2 receptor
The SARS-CoV-2 betacoronavirus uses its highly glycosylated trimeric Spike protein to bind
to the cell surface receptor angiotensin converting enzyme 2 (ACE2) glycoprotein and …
to the cell surface receptor angiotensin converting enzyme 2 (ACE2) glycoprotein and …
Tailor‐made amino acids and fluorinated motifs as prominent traits in modern pharmaceuticals
Structural analysis of modern pharmaceutical practices allows for the identification of two
rapidly growing trends: the introduction of tailor‐made amino acids and the exploitation of …
rapidly growing trends: the introduction of tailor‐made amino acids and the exploitation of …
Natural products and synthetic analogues against HIV: A perspective to develop new potential anti-HIV drugs
The human immunodeficiency virus (HIV) is responsible for acquired immune deficiency
syndrome (AIDS), one of the major pandemic diseases. Highly active antiretroviral therapy …
syndrome (AIDS), one of the major pandemic diseases. Highly active antiretroviral therapy …
Regulation of stem cell fate using nanostructure-mediated physical signals
Y Kong, J Duan, F Liu, L Han, G Li, C Sun… - Chemical Society …, 2021 - pubs.rsc.org
One of the major issues in tissue engineering is regulation of stem cell differentiation toward
specific lineages. Unlike biological and chemical signals, physical signals with adjustable …
specific lineages. Unlike biological and chemical signals, physical signals with adjustable …