[HTML][HTML] Fibromyalgia: recent advances in diagnosis, classification, pharmacotherapy and alternative remedies

ME Maffei - International journal of molecular sciences, 2020 - mdpi.com
Fibromyalgia (FM) is a syndrome that does not present a well-defined underlying organic
disease. FM is a condition which has been associated with diseases such as infections …

[HTML][HTML] Luteolin: A promising natural agent in management of pain in chronic conditions

F Ntalouka, A Tsirivakou - Frontiers in Pain Research, 2023 - frontiersin.org
Pain due to chronic conditions is a frequent and insufficiently addressed problem. Current
drug options for pain management (either in cases of chronic inflammatory conditions or …

Potential anxiolytic and antidepressant-like effects of luteolin in a chronic constriction injury rat model of neuropathic pain: Role of oxidative stress, neurotrophins, and …

T Mokhtari, M Lu, AEM El-Kenawy - International Immunopharmacology, 2023 - Elsevier
This study aimed to examine the effects of luteolin (LUT) on chronic neuropathic pain (NP)-
induced mood disorders (ie, anxiety and depression) by regulating oxidative stress …

Recent advances of thiazole hybrids in biological applications

M Gümüş, M Yakan, İ Koca - Future Medicinal Chemistry, 2019 - Taylor & Francis
Thiazoles have attracted much synthetic interest due to their wide variety of biological
properties and are important members of heterocyclic compounds. In recent years, studies …

[HTML][HTML] Ointment-Based Combination of Dittrichia viscosa L. and Marrubium vulgare L. Accelerate Burn Wound Healing

I Mssillou, A Agour, M Slighoua, M Chebaibi… - Pharmaceuticals, 2022 - mdpi.com
Burns constitute a major challenge in medical science, and plants can be part of the
solution. Dittrichia viscosa L.(Asteraceae) and Marrubium vulgare L.(Lamiaceae) are widely …

Flavone-based hydrazones as new tyrosinase inhibitors: Synthetic imines with emerging biological potential, SAR, molecular docking and drug-likeness studies

RI Alsantali, EU Mughal, N Naeem, MA Alsharif… - Journal of Molecular …, 2022 - Elsevier
Targeting tyrosinase (TYR), a key enzyme responsible for melanogenesis disorders, is a
well-known approach utilized for the development of melanogenesis inhibitor. A variety of …

Design, synthesis, and structural characterization of thioflavones and thioflavonols as potential tyrosinase inhibitors: In vitro and in silico studies

EU Mughal, J Ashraf, EM Hussein, Y Nazir… - ACS …, 2022 - ACS Publications
To find new potential tyrosinase inhibitors, a diverse range of 2-arylchromone-4-thione
derivatives (2a–2p) were designed and synthesized by employing a multistep strategy, and …

[PDF][PDF] Phytochemical and pharmacological properties of flavonols

A Sharma, P Sharma, HS Tuli, AK Sharma - eLS, 2018 - researchgate.net
Flavonoids are polyphenolic compounds, which are ubiquitous in nature and have been
categorised into flavonols, flavones, flavanones, isoflavones, catechins, anthocyanidins and …

Structure-based designing and synthesis of 2-phenylchromone derivatives as potent tyrosinase inhibitors: In vitro and in silico studies

J Ashraf, EU Mughal, RI Alsantali, RJ Obaid… - Bioorganic & Medicinal …, 2021 - Elsevier
The present study describes the discovery of novel inhibitors of mushroom tyrosinase
enzyme. For that purpose, a series of varyingly substituted 2-phenylchromone analogues 1 …

The effect of a topical formulation from Lawsonia inermis L.(henna) on pain intensity in patients with chronic sciatica: A randomized double-blind clinical trial

N Lavari, N Ostadrahimi, R Rahimi, M Raei… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Chronic sciatica (CS) is a common condition of disability
and pain. Lawsonia inermis L.(henna) is a medicinal plant that is commonly recommended …