Brain metastases occur commonly in patients with advanced solid malignancies. Yet, less is
known about brain metastases than cancer-related entities of similar incidence. Advances in …

The wide variety of treatment options that exist for glioblastoma, including surgery, ionizing
radiation, anti-neoplastic chemotherapies, anti-angiogenic therapies, and active or passive …

Since the introduction of chemoradiotherapy with temozolomide as the new standard of care
for patients with glioblastoma, there has been an increasing awareness of progressive and …

Localized proton magnetic resonance spectroscopy (MRS) of the human brain, first reported
more than 20 years ago, 1–3 is a mature methodology that is used clinically in many medical …

Treatment-induced CNS toxicity remains a major cause of morbidity in patients with cancer.
Advances in the design of safe radiation procedures have been counterbalanced by …

Both pseudo-phenomenona confuse the assessment of outcome of brain tumours in clinical
practice and in clinical trials. To overcome these issues, alternative endpoints and response …

Differentiating treatment-induced necrosis from tumor recurrence is a central challenge in
neuro-oncology. These 2 very different outcomes after brain tumor treatment often appear …

Standard MR imaging and CT are routinely used for anatomic diagnosis in brain tumors.
Pretherapy planning and posttreatment response assessments rely heavily on gadolinium …

Diffusion-weighted magnetic resonance (MR) imaging and perfusion MR imaging are
advanced techniques that provide information not available from conventional MR imaging …

Abstract INTRODUCTION: Contrast-enhanced MRI (CE-MRI) represents the current
mainstay for monitoring treatment response in glioblastoma multiforme (GBM), based on the …